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Inosine 3'-phosphate, also known as Imp3', is a nucleoside monophosphate that plays a crucial role in cellular metabolism. It is formed by the phosphorylation of inosine, a nucleoside composed of hypoxanthine and ribose. Inosine 3'-phosphate is involved in various biochemical processes, including the synthesis of nucleic acids and energy production. It is an important intermediate in the purine salvage pathway, which recycles purines to produce nucleotides for DNA and RNA synthesis. Additionally, it can be converted to other nucleotides, such as adenosine 3'-phosphate (AMP) and guanosine 3'-phosphate (GMP), through a series of enzymatic reactions. Inosine 3'-phosphate is also a precursor for the synthesis of inositol, a key component of cell membranes and a second messenger in signal transduction pathways. Its role in these processes highlights the significance of inosine 3'-phosphate in maintaining cellular homeostasis and function.

572-47-4

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572-47-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 572-47-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,7 and 2 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 572-47:
(5*5)+(4*7)+(3*2)+(2*4)+(1*7)=74
74 % 10 = 4
So 572-47-4 is a valid CAS Registry Number.

572-47-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 3'-inosine monophosphate

1.2 Other means of identification

Product number -
Other names inosine-3'-monophosphate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:572-47-4 SDS

572-47-4Downstream Products

572-47-4Relevant academic research and scientific papers

Phosphorylation and dephosphorylation of polyhydroxy compounds by class A bacterial acid phosphatases

Tanaka, Naoko,Hasan, Zulfiqar,Hartog, Aloysius F.,Van Herk, Teunie,Wever, Ron

, p. 2833 - 2839 (2007/10/03)

Nonspecific acid phosphatases share a conserved active site with mammalian glucose-6-phosphatases (G6Pase). In this work we examined the kinetics of the phosphorylation of glucose and dephosphorylation of glucose-6-phosphate (G6P) catalysed by the acid phosphatases from Shigella flexneri (PhoN-Sf) and Salmonella enterica (PhoN-Se). PhoN-Sf is able to phosphorylate glucose regiospecifically to G6P, glucose-1-phosphate is not formed. The Km for glucose using pyrophosphate (PPi) as a phosphate donor is 5.3 mM at pH 6.0. This value is not significantly affected by pH in the pH region 4-6. The Km value for G6P by contrast is much lower (0.02 mM). Our experiments show these bacterial acid phosphatases form a good model for G6Pase. We also studied the phosphorylation of inosine to inosine monophosphate (IMP) using PPi as the phosphate donor. PhoN-Sf regiospecifically phosphorylates inosine to inosine-5′-monophosphate whereas PhoN-Se produces both 5′IMP and 3′IMP. The data show that during catalysis an activated phospho-enzyme intermediate is formed that is able to transfer its phosphate group to water, glucose or inosine. A general mechanism is presented of the phosphorylation and dephosphorylation reaction catalysed by the acid phosphatases. Considering the nature of the substrates that are phosphorylated it is likely that this class of enzyme is able to phosphorylate a wide range of hydroxy compounds.

PHOSPHORYLATION OF INOSINE WITH CYCLO-TRIPHOSPHATE

Tsuhako, Mitsutomo,Fujimoto, Mayumi,Ohashi, Shigeru

, p. 849 - 852 (2007/10/02)

Phosphorylation of inosine with cyclo-triphosphate (P3m) in aqueous solution was studied by means of anion-exchange chromatography and high performance liquid chromatography.P3m reacted with inosine at 70 deg C and room temperature and at pH 12 to form inosine 2'- and 3'-monophosphates.The yields of 2'- and 3'-monophosphates were about 33 and 26 percent, respectively.

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