57221-60-0

Basic information

• Product Name: 2-hydroxy-4-butoxyacetophenone
• Synonyms: 2-hydroxy-4-butoxyacetophenone
• CAS NO: 57221-60-0
• Molecular Weight: 208.257
• Mol File: 57221-60-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-hydroxy-4-butoxyacetophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hydroxy-4-butoxyacetophenone(57221-60-0)
• EPA Substance Registry System: 2-hydroxy-4-butoxyacetophenone(57221-60-0)

Safety Data

• Hazardous Substances Data: 57221-60-0(Hazardous Substances Data)

Upstream product

• 109-65-9 1-bromo-butane 
• 89-84-9 2',4'-dihydroxy-4-acetophenone 
• 108-46-3 recorcinol 
• 542-69-8 1-iodo-butane 

Downstream Products

• 136136-01-1 5-Butoxy-2-{1-[(E)-butylimino]-ethyl}-phenol 
• 136136-00-0 4-[1-(4-Butoxy-2-hydroxy-phenyl)-eth-(E)-ylideneamino]-butyric acid 
• 101888-76-0 1-(4-butoxy-2-hydroxy-phenyl)-3-piperidino-propan-1-one; hydrochloride 

Relevant articles and documents

Microwave-assisted synthesis and antifungal activity of novel coumarin derivatives: Pyrano[3,2-c]chromene-2,5-diones

A series of novel fused coumarin analogues pyrano[3,2-c]chromene-2,5-diones have been synthesized through an optimized microwave-assisted protocol. All target compounds were tested and evaluated for their antifungal activity against Botrytis cinerea, Colletotrichum copsica, Alternaria solani, Gibberella zeae and Rhizoctorzia solani. The bioassay results indicated that some of the compounds exhibited potent antifungal activities at concentration less than 50 ppm. For the compounds 5d, 6c and 7b, EC50 values against B. cinerea were as low as 0.141, 0.082 and 0.091 μM, respectively, which represents better antifungal activity than that of the commonly used fungicide Azoxystrobin. Compounds 5d (57%) and 6c (55%) also exhibited more effective control than Azoxystrobin (44%) against Colletotrichum capsica.

2-acetylphenol analogs as potent reversible monoamine oxidase inhibitors

Based on a previous report that substituted 2-acetylphenols may be promising leads for the design of novel monoamine oxidase (MAO) inhibitors, a series of C5-substituted 2-acetylphenol analogs (15) and related compounds (two) were synthesized and evaluate

SYNTHESIS AND MESOMORPHIC PROPERTIES OF THREE HOMOLOGOUS SERIES OF 4,4 prime -DIALKOXY- alpha , alpha prime -DIMETHYLBENZALAZINES.

Three homologous series of alpha , alpha prime -dimethylbenzalazines have been synthesized: 4,4 prime -dialkoxy- alpha , alpha prime -dimethylbenzalazines, 4,4 prime -dialkoxy-2,2 prime -dihydroxy- alpha , alpha prime -dimethylbenzalazines, and 4,4 prime -dialkoxy-2-hydroxy- alpha , alpha prime -dimethylbenzalazines. The influence of molecular structure on the mesomorphic properties was studied. Mesomorphic properties and phase transitions were determined using a polarizing hot-stage microscope and a differential scanning calorimeter. The introduction of one or two hydroxyl groups in position 2- or 2-and 2 prime -of the aromatic rings (4,4 prime -dialkoxy-2-hydroxy- alpha , alpha prime -dimethylbenzalazines and 4,4 prime -dialkoxy-2,2 prime -dihydroxy- alpha , alpha prime -dimethylbenzalazines respectively) gives molecules with an excellent mesogenic quality, and all the prepared compounds of these series exhibit mesomorphism. Compounds of the series with two hydroxyl groups exhibit smectic polymorphism which is not so in the case of the compounds of the other series. The melting temperatures are systematically lower for the 4,4 prime -dialkoxy-2-hydroxy- alpha , alpha prime -dimethylbenzalazines than for the other two series.