57235-35-5

Basic information

• Product Name: 2-Mercapto-4,6-dimethoxypyrimidine
• Synonyms: PYRIMIDINE, 4,6-DIMETHOXY-2-(METHYLTHIO)-;4,6-DIMETHOXY-2-THIOMETHYLPYRIMIDINE;4,6-DIMETHOXY-2-METHYLMERCAPTO PYRIMIDINE;4,6-DIMETHOXY-2-METHYLMERCAPYRIMIDINE;2-Mercapto-4,6-Dimethoxy-Pyrimidine;2(1H)-PYRIMIDINETHIONE,4,6-DIMETHOXY;4,6-Dimethoxy-2-mercaptopyrimidine
• CAS NO: 57235-35-5
• Molecular Formula: C₆H₈N₂O₂S
• Molecular Weight: 172.2
• Mol File: 57235-35-5.mol
• Article Data: 2

Chemical Properties

• Melting Point: 56-60 °C(lit.)
• Boiling Point: 250.9oC at 760 mmHg
• Flash Point: 105.6oC
• Appearance: /
• Density: 1.32g/cm3
• Vapor Pressure: 0.0211mmHg at 25°C
• Refractive Index: 1.584
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 8.11±0.10(Predicted)
• CAS DataBase Reference: 2-Mercapto-4,6-dimethoxypyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Mercapto-4,6-dimethoxypyrimidine(57235-35-5)
• EPA Substance Registry System: 2-Mercapto-4,6-dimethoxypyrimidine(57235-35-5)

Safety Data

• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 57235-35-5(Hazardous Substances Data)

Usage

General Description

2-Mercapto-4,6-dimethoxypyrimidine, also known as MDP, is a chemical compound with a molecular formula of C6H8N2O2S. It is a derivative of pyrimidine and contains a thiol group and two methoxy groups attached to the pyrimidine ring. MDP is a key intermediate in the synthesis of pharmaceuticals and agrochemicals, and it is commonly used in the production of various bioactive compounds. It has been studied for its potential antifungal, antibacterial, and anti-inflammatory properties, making it a valuable building block in the development of new drugs and agricultural products. Additionally, MDP has been investigated for its potential role as a corrosion inhibitor and as an antioxidant in polymer materials.

InChI:InChI=1/C6H8N2O2S/c1-9-4-3-5(10-2)8-6(11)7-4/h3H,1-2H3,(H,7,8,11)

Upstream product

• 113583-35-0 4,6-dimethoxypyrimidin-2-yl methyl sulfone 
• 35144-22-0 4,6-dimethyl-2-methylsulfonylpyrimidine 
• 13223-25-1 2-chloro-4,6-dimethoxypyrimidine 

Downstream Products

• 170296-17-0 methyl 3-benzyloxy-3-phenyl-2-(4,6-dimethoxypyrimidin-2-ylthio)-butyrate 
• 1334214-42-4 C₂₂H₂₄N₆O₂S 
• 90905-46-7 4,6-dimethoxy-2-(methylsulfanyl)pyrimidine 
• 123342-93-8 2-chloro-6-[(4,6-dimethoxypyrimidin-2-yl)thio]benzoic acid 

Relevant articles and documents

7-(4,6-dimethoxypyrimidinyl)oxy- and -thiophthalides as novel herbicides: Part 1. CGA 279 233: A new grass-killer for rice

A series of novel types of 7-(4,6-dimethoxypyrimidin-2-yl)oxy - and -thio-3-methyl-1 (3H)-isobenzofuranones were discovered at Dr R Maag AG. From the thio-isobenzofuranyl series, CGA 279 233 - BSI-proposed common name pyriftalid - was chosen for further development as a grass herbicide for use in rice. General synthetic approaches to these new phthalic acid-derived compounds are given, with emphasis on the synthesis of pyriftalid and its physico-chemical behaviour.