57243-82-0Relevant academic research and scientific papers
Synthesis of certain 6-benzyl-5-methylthieno[2,3-d]pyrimidines
El-Meligie
, p. 1126 - 1131 (2007/10/03)
Thieno[2,3-d]pyrimidines 3a, b and 6 have been obtained via the reaction of 1 with formic acid, acetic anhydride and formamide respectively. Cyclization of 1 with arylisothiocyanates at different reaction conditions yield 4-thioxothieno[2,3-d]pyrimidines 8a, b and 4-imino-2-thioxothieno[2,3-d]pyrimidines 9a, b through the formation of the thioureas 7a, b. Treatment of 1 with CS2 in pyridine at room temperature and reflux temperature respectively afford the thioxothieno-(1, 3)-thiazine 11 and dithioxothienopyrimidine 12. Compound 11 is converted into the thienopyrimidines 9a-d by reaction with aromatic amines.
