57264-52-5

Upstream product

• 109-65-9 1-bromo-butane 
• 5428-54-6 2-methyl-5-nitrophenol 
• 542-69-8 1-iodo-butane 
• 2372-45-4 sodium butanolate 
• 778-28-9 butyl para-toluenesulfonate 
• 95-53-4 o-toluidine 
• 99-55-8 2-methyl-5-nitroaniline 

Downstream Products

• 267897-01-8 4-amino-2-butoxy-benzaldehyde 
• 103796-30-1 2-butoxy-4-nitro-benzoic acid 
• 100514-27-0 3-Butoxy-4-methylbenzolamin-Hydrochlorid 
• 1312613-05-0 (2-n-butoxy-4-nitrobenzyl)triphenylphosphonium bromide 
• 61566-62-9 4-amino-2-butoxy-benzoic acid 
• 91289-92-8 4-(2-Amino-4-butoxy-5-methylphenyldiazenyl)-N-methylphthalimid 
• 57264-53-6 (α-bromo-5-nitroo-tolyl) butyl ether 

Relevant academic research and scientific papers

Peroxisome proliferator-activated receptor agonists with phenethylphenylphthalimide skeleton derived from thalidomide-related liver X receptor antagonists: Relationship between absolute configuration and subtype selectivity

Introduction of an alkylcarboxylic acid unit, which is a partial structure of endogenous peroxisome proliferator-activated receptor (PPAR) ligands, into a phenethylphenylphthalimide skeleton, which possesses liver X receptor (LXR) antagonistic activity, afforded novel PPAR ligands. The results of structure-activity relationship analysis and docking studies led us to the potent PPAR agonists 13c-e. The absolute configuration of 13c-e affects the PPAR subtype selectivity.

Electron Rich Heterocycles as Donor Groups in Fluorescent Dyes

The synthesis of N-methylphthalimides substituted with the donor groups pyrazole, triazole, benzotriazole, and naphthotriazole in position 4 is described (17, 18, 14, 12).The substituent constants of these groups are obtained by alkaline hydrolysis of the corresponding phthalimide dyes.Their solvatochromism in absorption and fluorescence gives information about charge distribution in ground- and excited state.