57264-60-5

Upstream product

• 24155-42-8 1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethan-1-ol 
• 46503-52-0 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanone 
• 4252-78-2 2,2',4'-trichloroacetophenone 
• 1777-82-8 (2,4-dichlorophenyl)methanol 
• 112-29-8 1-bromo dodecane 
• 22916-47-8 miconazole 

Relevant academic research and scientific papers

Anti-staphylococcal biofilm activity of miconazoctylium bromide

We designed and synthesized miconazole analogues containing a substituted imidazolium moiety. The structural modification of the miconazole led to a compound with high potency to prevent the formation and disrupt bacterial biofilms, as a result of accumulation in the biofilm matrix, permeabilization of the bacterial membrane and generation of reactive oxygen species in the cytoplasm.

Imidazolium salts

Novel quaternary imidazolium salts substituted on one nitrogen of the imidazolium cation with a EQU1 group in which each A is an aryl radical and B is an aliphatic, aryl-substituted aliphatic or aromatic radical, said salts being useful as antimicrobial agents.