57266-86-1Relevant academic research and scientific papers
A Simple Route to α,β-Unsaturated Aldehydes from Prop-2-ynols
Ma, Dawei,Lu, Xiyan
, p. 890 - 891 (2007/10/02)
2-Ynols can be isomerised stereoselectively to (2E)-enals with a ruthenium complex as catalyst.
Cumulated Ylides, XII. A Stereoselective Synthetic Method for (Z)-α,β-Unsaturated Aldehydes
Bestmann, Hans Juergen,Roth, Kurt,Ettlinger, Manfred
, p. 161 - 171 (2007/10/02)
(2-Ethoxyvinyl)triphenylphosphonium bromide (5) is converted with sodium amide into the corresponding phosphaallenylide 6 which adds ethanol forming the ylide 7. 7 is also obtained by the reaction of 5 with sodium ethanolate.The Wittig reaction of 7 with aldehydes 2 proceeds with high (Z)-stereoselectivity to give (Z)-α,β-unsaturated acetals 8 which are cleaved under well defined conditions with p-toluenesulfonic acid or with wet silica gel to (Z)-α,β-unsaturated aldehydes 9.
REINVESTIGATION OF THE GRIGNARD REACTIONS WITH FORMIC ACID. A CONVENIENT METHOD FOR PREPARATION OF ALDEHYDES
Sato, Fumie,Oguro, Kaoru,Watanabe, Hiroshi,Sato, Masao
, p. 2869 - 2872 (2007/10/02)
Grignard reagents react with formic acid in tetrahydrofuran to produce aldehydes in relatively good yields.Various aldehydes such as alkyl, aryl, allyl, benzyl and vinyl aldehydes were prepared from the corresponding Grignard reagents.The reaction with vinyl Grignard reagents proceeded with retention of configuration.
