572909-07-0Relevant academic research and scientific papers
N-alkoxypyrazoles as biomimetics for the alkoxyphenyl group in tamoxifen
Wenckens, Martin,Jakobsen, Palle,Vedso, Per,Huusfeldt, Per Olaf,Gissel, Birgitte,Barfoed, Marianne,Brockdorff, Bettina Lundin,Lykkesfeldt, Anne E.,Begtrup, Mikael
, p. 1883 - 1899 (2007/10/03)
The preparation of a series of novel analogues of the selective antiestrogen tamoxifen is reported. 1Z-alkoxyphenyl group in tamoxifen has been replaced by a N-alkoxypyrazole, while functionalised phenyl groups or heteroaromatics were introduced at the 2Z
