57295-79-1

Upstream product

• 6938-68-7 2-methyl-thiosemicarbazide 
• 100-07-2 4-methoxy-benzoyl chloride 

Downstream Products

• 751459-12-8 (6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-methoxyimino]-acetylamino}-3-[5-(4-methoxy-phenyl)-2-methyl-2H-[1,2,4]triazol-3-ylsulfanylmethyl]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 
• 177713-80-3 (6R,7R)-7-Amino-3-[5-(4-methoxy-phenyl)-2-methyl-2H-[1,2,4]triazol-3-ylsulfanylmethyl]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 
• 57295-80-4 5-(4-methoxy-phenyl)-2-methyl-2,4-dihydro-[1,2,4]triazole-3-thione 

Relevant academic research and scientific papers

Synthesis and structure-activity relationship of C-3 substituted triazolylthiomethyl cephems

A series of C-3 substituted triazolylthiomethyl cephems with an aminothiazolemethoxyiminoacetamido side chain at C-7 were synthesized and tested for antimicrobial activity against clinically-relevant isolates. The compound with 3-pyridyl at C-5 and methyl at N-4 of the triazole moiety exhibited good antibacterial activity against both Gram-positive and Gram-negative bacteria, with the exception of pseudomonas spp against which none of the derivatives exhibited favorable activity.