57339-11-4

Basic information

• Product Name: N1-(3,5-DICHLOROPHENYL)-2-BROMOACETAMIDE
• Synonyms: N1-(3,5-DICHLOROPHENYL)-2-BROMOACETAMIDE;N-(BROMOACETYL)-3,5-DICHLOROANILINE;2-bromo-N-(3,5-dichlorophenyl)acetamide
• CAS NO: 57339-11-4
• Molecular Formula: C₈H₆BrCl₂NO
• Molecular Weight: 282.95
• Mol File: 57339-11-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 399.2 °C at 760mmHg
• Flash Point: 195.2 °C
• Appearance: /
• Density: 1.772 g/cm³
• Vapor Pressure: 1.4E-06mmHg at 25°C
• Refractive Index: 1.647
• CAS DataBase Reference: N1-(3,5-DICHLOROPHENYL)-2-BROMOACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N1-(3,5-DICHLOROPHENYL)-2-BROMOACETAMIDE(57339-11-4)
• EPA Substance Registry System: N1-(3,5-DICHLOROPHENYL)-2-BROMOACETAMIDE(57339-11-4)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 57339-11-4(Hazardous Substances Data)

Usage

General Description

N1-(3,5-Dichlorophenyl)-2-bromoacetamide is a chemical compound with the molecular formula C8H6BrCl2NO. It is a bromoacetamide derivative with a 3,5-dichlorophenyl group attached to the nitrogen atom. N1-(3,5-DICHLOROPHENYL)-2-BROMOACETAMIDE is used primarily in pharmaceutical and chemical research as an intermediate or building block for the synthesis of various biologically active compounds. Its applications include the development of potential anti-cancer and antifungal agents. N1-(3,5-Dichlorophenyl)-2-bromoacetamide is also of interest in the study of molecular interactions and in the development of new chemical reactions. Its structure and properties make it a valuable tool in scientific and medical research.

InChI:InChI=1/C8H6BrCl2NO/c9-4-8(13)12-7-2-5(10)1-6(11)3-7/h1-3H,4H2,(H,12,13)

Upstream product

• 598-21-0 2-Bromoacetyl bromide 
• 626-43-7 3,5-Dichloroaniline 
• 22118-09-8 2-bromoacetyl chloride 

Downstream Products

• 1090383-87-1 C₂₀H₂₃Cl₂N₃O 
• 1158613-46-7 C₁₂H₁₅Cl₂N₃O*ClH 
• 889600-75-3 C₁₉H₂₁Cl₂N₃O 
• 1401333-59-2 C₁₇H₂₃Cl₂N₃O₃ 
• 647031-44-5 C₁₈H₁₉Cl₂N₃O 
• 753028-93-2 C₂₈H₃₅Cl₂N₃O₂ 

Relevant articles and documents

AUTOTAXIN INHIBITOR COMPOUNDS

Described herein are compounds that are autotaxin inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with autotaxin activity.

The design and synthesis of 1,4-substituted piperazine derivatives as triple reuptake inhibitors

Novel 1,4-substituted piperazine derivatives 5, Series A and B were designed by fragment analysis and molecular modification of 4 selected piperazine-containing compounds which possess antidepressant activity. We synthesized new 39 analogues of Series A and 10 compounds of Series B, respectively. The antidepressant screening against DA, NE, and serotonin neurotransmitter uptake inhibition was carried out using the Neurotransmitter Transporter Uptake Assay Kit. The compounds in Series B showed relatively higher reuptake inhibitory activity for SERT, NET, and DAT than those in Series A. The length of spacer between the central piperazine core and the terminal phenyl ring substituted at the piperazine ring in Series B seems to exert an important role in the activity.