57346-40-4Relevant academic research and scientific papers
Enantioselective mukaiyama-aldol reaction between enol silanes and ketomalonate catalyzed by the copper(II) complex of tips-substituted bis-oxazoline
Desimoni, Giovanni,Faita, Giuseppe,Livieri, Alessandro,Ponta, Laura
, p. 669 - 677 (2012)
The stable complex [(4'S,5'S)-4b/Cu(Tf)2/H2O] (5), obtained from TIPS-Box and Copper triflate, catalyzes enantioselectively the Mukaiyama-aldol reactions between two silyl enol ethers (1a,b) and diethyl ketomalonate (2). Yields are v
AZABICYCLIC(THIO)AMIDES AS FUNGICIDAL COMPOUNDS
-
Page/Page column 151, (2021/11/26)
The present invention relates to azabicyclic (thio)amide compounds and the uses thereof for controlling phytopathogenic microorganisms such as phytopathogenic fungi. It also relates to processes and intermediates for preparing these compounds
METALLOENZYME INHIBITOR COMPOUNDS
-
Paragraph 1400; 1401; 1402, (2018/07/29)
Provided are compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
Synthetic studies on CP-225,917 and CP-263,114: Concise synthesis of the bicyclic core using an intramolecular Mukaiyama aldol reaction
Armstrong, Alan,Critchley, Trevor J.,Gourdel-Martin, Marie-Edith,Kelsey, Richard D.,Mortlock, Andrew A.
, p. 1344 - 1350 (2007/10/03)
A concise synthesis of the bicyclo[4.3.1]dec-1(9)-en-10-one core of the natural products CP-225,917 and CP-263,114 is reported, employing an intramolecular Mukaiyama aldol cyclisation as a key step.
Synthesis of the bicyclo[4.3.1]decenone core of CP-225,917 and CP-263,114
Armstrong, Alan,Critchley, Trevor J.,Mortlock, Andrew A.
, p. 552 - 553 (2007/10/03)
The bicyclo[4.3.1]decenone core of the ras-farnesyl protein transferee inhibitors CP-225,917 and CP-263,114 is prepared in 6 steps from cyclohexanone. The key step is an intramolecular Mukaiyama aldol reaction.
ENE REACTION OF THE ACTIVE C=N AND C=O GROUP WITH KETONES. A NOVEL SYNTHESIS OF γ-OXO-α-AMINO- AND γ-OXO-α-HYDROXY-ACIDS.
Achmatowicz, Osman,Pietraszkiewicz, Marek
, p. 4323 - 4326 (2007/10/02)
Thermal reaction of butyl N-(p-toluenesulphonyl)iminoacetate and diethyl mesoxalate with ketones leads to the derivatives of γ-oxo-α-amino-acids and γ-oxo-α-hydroxy-acids, respectively.
