5736-06-1

Usage

Uses

Used in Pharmaceutical Industry:
2,2-Dimethyl-1,3-dioxolane-4-carboxylic acid is used as a synthetic intermediate for the production of pharmaceuticals. It serves as a key building block in the synthesis of various drugs, contributing to the development of new medications with potential therapeutic benefits.
Used in Agrochemical Industry:
2,2-Dimethyl-1,3-dioxolane-4-carboxylic acid is also used as a synthetic intermediate in the production of agrochemicals. It plays a crucial role in the synthesis of various agrochemical compounds, helping to develop new products for agricultural applications, such as pesticides and herbicides.
Safety Precautions:
It is important to handle 2,2-Dimethyl-1,3-dioxolane-4-carboxylic acid with caution, as it is a potential irritant. Contact with skin and eyes can cause irritation, so appropriate safety measures should be taken during its use and handling in both pharmaceutical and agrochemical industries.

Upstream product

• 134036-81-0 (4S,5S)-5-[(R)-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-hydroxy-methyl]-2,2-dimethyl-[1,3]dioxolane-4-carboxylic acid anion 
• 5736-03-8 (d,l) isopropylidene glyceraldehyde 
• 7306-64-1 2,3,5,6-di-O-isopropylidene-D-mannono-1,4-lactone 
• 14131-84-1 2,3:5,6-di-O-isopropylidene-α-D-mannofuranose 
• 108865-84-5 methyl 2,2-dimethyl-1,3-dioxolane-4-carboxylate 
• 100-79-8 (R,S)-2,2-dimethyl-1,3-dioxolane-4-methanol 

Downstream Products

• 108865-84-5 methyl 2,2-dimethyl-1,3-dioxolane-4-carboxylate 
• 90493-96-2 2,2-dimethyl-1,3-dioxolane-4-carboxylic acid chloride 
• 158091-91-9 C₁₇H₂₃NO₄ 
• 1026631-82-2 4-(1-Hydroxy-2-phenylselanyl-ethyl)-2,2-dimethyl-[1,3]dioxolane-4-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Synthesis of phospholipids on a glyceric acid scaffold: Design and preparation of phospholipase A2 specific substrates

Synthesis of a new series of phospholipid analogues to serve as activity-based probes of secretory phospholipase A2 enzymes is reported. The synthesis is based upon (1) preparation of long-chain esters and amides of glyceric acid, followed by (

ARYLMETHYLENE HETEROCYCLIC COMPOUNDS AS KV1.3 POTASSIUM SHAKER CHANNEL BLOCKERS

A compound of Formula (I) or a pharmaceutically acceptable salt thereof is described, wherein the substituents are as defined herein. Pharmaceutical compositions comprising the same and method of using the same are also described.

Electrochemical Oxidation of Alcohols and Aldehydes to Carboxylic Acids Catalyzed by 4-Acetamido-TEMPO: An Alternative to "anelli" and "pinnick" Oxidations

An electrocatalytic method has been developed to oxidize primary alcohols and aldehydes to the corresponding carboxylic acids using 4-acetamido-2,2,6,6-tetramethylpiperidin-1-oxyl (ACT) as a mediator. The method successfully converts benzylic, aliphatic, heterocyclic, and other heteroatom-containing substrates to the corresponding carboxylic acids in aqueous solution at room temperature. The mild conditions enable retention of stereochemistry adjacent to the site of oxidation, as demonstrated in a 40 g-scale synthesis of a precursor to levetiracetam, a medication used to treat epilepsy.

[4-(1, 3, 3-TRIMETHYL-2-OXO-3, 4-DIHYDRO-1H-QUINOXALIN-7-YL) PHENOXY]ETHYLOXY COMPOUND OR SALT THEREOF

The present invention relates to a novel [4-(1,3,3-trimethyl-2-oxo-3,4-dihydro-1H-quinoxalin-7-yl)phenoxy]ethyloxy compound or a salt thereof. The compound or a salt thereof of the present invention has a glucocorticoid receptor agonist activity, and is u

SPIROCYCLIC HAT INHIBITORS AND METHODS FOR THEIR USE

Compounds having a structure of Formula (IX) or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof, wherein R1, R2a, R2b, R3a, R3b, R4a, R4b, Q1----Q2, R6, R7, A, B, W, x, and y are as defined herein and are provided. Pharmaceutical compositions comprising such compounds and methods for treating various HAT-related conditions or diseases, including cancer, by administration of such compounds are also provided.

Catalyzed dehydrogenative coupling of primary alcohols with water, methanol, or amines

A working partnership: Metal-ligand cooperativity is responsible for the high activity of the rhodium amido complex 1 in the dehydrogenative coupling of primary alcohols with water, methanol, or amines, including ammonia (see scheme), to give carboxylic acids, methyl carboxylates, or amides, respectively. The catalysis proceeds under mild reaction conditions in the presence of a recyclable hydrogen acceptor A. The multistep mechanism was elucidated by computational methods. (Chemical Equation Presented)

Method for producing carbonyl compound

[summary][PROBLEM TO BE SOLVED]: To provide a method for effectively producing carbonyl compound from alcohol using a ruthenium compound as an oxidation catalyst which can apply to various alcoholic compounds as starting materials, and to provide a method for effectively producing the carbonyl compound in high yield with decomposing neither the alcohol nor the produced carbonyl compound.[SOLUTION]: The method for producing carbonyl compound comprises the oxidative reaction process of alcohol using N-haloamide compound or N-haloimide compound in the presence of ruthenium compound of catalytic amount in the solvent containing organic solvent not substantially oxidized with the ruthenium compound The solvent used is solvent containing organic solvents other than the carboxylic acid; mixed solvent of pH5-14 containing organic solvent and water; or organic solvent containing base.

UREA-, GLYCERATE- AND, HYDROXYAMIDE-HEADED HYDROCARBON CHAIN LYOTROPIC PHASES FORMING SURFACTANTS

The invention provides a compound containing a head group based on urea, glycerol or glycerate and a tail selected from the group consisting of a branched alkyl chain, a branched alkyloxy chain or an alkenyl chain. The compounds may be used as surfactants to form a lyotropic phase that is stable in excess polar solution.

A practical RuCl3-catalyzed oxidation using trichlproisocyanuric acid as a stoichiometric oxidant under mild nonacidic conditions

The combined use of catalytic RuCl3 (1.0 mol %) and stoichiometric trichloroisocyanuric acid (TCCA; 1.0 equiv) in the presence of n-Bu4NBr (2.0 mol %) and K2CO3 (3.0 equiv) in 1:1 MeCN/H2O at 25-45°C allows smooth oxidation of primary alcohols to carboxylic acids. Secondary alcohols can be oxidized to ketones when using the same set of the reagents in 1:1 MeCN/ H2O or 1:1 AcOEt/H2O. By proceeding under the nonacidic biphasic conditions dispensing with hazardous reagents, the oxidation reactions are applicable to structurally diverse alcohols, easy to work up, environmentally benign, and basically high-yielding.

Investigation of glycerol incorporation into soraphen A

Glycerol has been incorporated mid-chain into the polyketide soraphen A 1 at C-3,4 and C-11,12; the pro-(S)-hydroxymethyl group of glycerol is lost and one of the hydrogens in the pro-(R)-hydroxymethyl group is retained at C-11 which excludes hydroxymalonate as the immediate precursor to the vicinal methoxy groups at C-11,12.