5736-89-0

Basic information

• Product Name: 4'-BUTOXYACETOPHENONE
• Synonyms: 1-(4-butoxyphenyl)-ethanon;Acetophenone, 4'-butoxy-;Ethanone, 1-(4-butoxyphenyl)-;1-(4-butoxyphenyl)ethan-1-one;Bufexamac Imp. (EP);4-(N-BUTOXY)ACETOPHENONE;4'-N-BUTOXYACETOPHENONE;4'-BUTOXYACETOPHENONE
• CAS NO: 5736-89-0
• Molecular Formula: C₁₂H₁₆O₂
• Molecular Weight: 192.25
• EINECS: 227-248-4
• Product Categories: Aromatic Acetophenones & Derivatives (substituted);Adehydes, Acetals & Ketones;Anisoles, Alkyloxy Compounds & Phenylacetates;Acetophenones (Building Blocks for Liquid Crystals);Building Blocks for Liquid Crystals;Functional Materials;C11 to C12;Carbonyl Compounds;Ketones;Building Blocks;C11 to C12;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks
• Mol File: 5736-89-0.mol
• Article Data: 33

Chemical Properties

• Melting Point: 25-27°C
• Boiling Point: 302-304 °C(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.017 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.000888mmHg at 25°C
• Refractive Index: n20/D 1.531(lit.)
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: very faint turbidity in Methanol
• BRN: 637894
• CAS DataBase Reference: 4'-BUTOXYACETOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-BUTOXYACETOPHENONE(5736-89-0)
• EPA Substance Registry System: 4'-BUTOXYACETOPHENONE(5736-89-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/38
• Safety Statements: 26-36
• WGK Germany: 3
• TSCA: Yes
• HazardClass: IRRITANT
• Hazardous Substances Data: 5736-89-0(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 5736-89-0 differently. You can refer to the following data:
1. 1-(4-butoxyphenyl)ethanone is a useful research chemical.
2. 4′-Butoxyacetophenone (4-Butoxyacetophenone) may be used to synthesize:3,5-di-(4-butoxyphenyl)-1H-pyrazole(E)-1-(4-butoxyphenyl)-3-phenylprop-2-en-1-one5-aryl-6H-1,3,4-thiadiazine

Chemical Properties

Colorless liquid

General Description

4′-Butoxyacetophenone is a mildly electron-enriched phenylmethylketone.

InChI:InChI=1/C12H16O2/c1-3-4-9-14-12-7-5-11(6-8-12)10(2)13/h5-8H,3-4,9H2,1-2H3

Upstream product

• 1126-79-0 n-butyl phenyl ether 
• 108-24-7 acetic anhydride 
• 75-36-5 acetyl chloride 
• 99-89-8 4-Isopropylphenol 
• 28530-37-2 1-butoxy-4-isopropylbenzene 
• 2550-26-7 4-Phenyl-2-butanone 
• 105365-51-3 4-butoxyphenylboronic acid 
• 3524-86-5 1-(4-(4-bromobutoxy)phenyl)ethan-1-one 
• 123-07-9 4-Ethylphenol 
• 99-71-8 4-(1-methylpropyl)phenol 
• 36160-80-2 1-butoxy-4-(1-methylpropyl)benzene 
• 69497-83-2 4-acetylphenyl mesylate 
• 71-36-3 butan-1-ol 
• 99-93-4 4-Hydroxyacetophenone 

Downstream Products

• 78382-09-9 C₁₃H₂₀N₄OS 
• 91553-11-6 α-<4-Butyloxy-phenyl>-aethylamin 
• 642082-94-8 2-acetyl-4'-n-butoxyacetophenone 
• 1243257-44-4 C₁₆H₂₅NO₃ 
• 1243257-35-3 2-[2-(4-butoxyphenylmorpholino-4-yl)ethyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-acetate] hydrochloride 
• 18099-71-3 2-(1-(4-butoxyphenyl)ethylidene)hydrazine-1-carbothioamide 
• 101356-81-4 1-(4-butoxyphenyl)-3-(dimethylamino)propan-1-one 

Relevant articles and documents

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Selective Activation of Unstrained C(O)-C Bond in Ketone Suzuki-Miyaura Coupling Reaction Enabled by Hydride-Transfer Strategy

A Rh(I)-catalyzed ketone Suzuki-Miyaura coupling reaction of benzylacetone with arylboronic acid is developed. Selective C(O)-C bond activation, which employs aminopyridine as a temporary directing group and ethyl vinyl ketone as a hydride acceptor, occurs on the alkyl chain containing a β-position hydrogen. A series of acetophenone products were obtained in yields up to 75%.

Development of Trifluoromethanesulfonic Acid-Immobilized Nitrogen-Doped Carbon-Incarcerated Niobia Nanoparticle Catalysts for Friedel-Crafts Acylation

Heterogeneous trifluoromethanesulfonic acid-immobilized nitrogen-doped carbon-incarcerated niobia nanoparticle catalysts (NCI-Nb-TfOH) that show excellent catalytic performance with low niobium loading (1 mol %) in Friedel-Crafts acylation have been developed. These catalysts exhibit higher activity and higher tolerance to catalytic poisons compared with the previously reported TfOH-treated NCI-Ti catalysts, leading to a broader substrate scope. The catalysts were characterized via spectroscopic and microscopic studies.