573693-07-9

Upstream product

• 645-08-9 Isovanillic acid 
• 358-23-6 trifluoromethylsulfonic anhydride 
• 6702-50-7 3-hydroxy-4-methoxybenzoate 

Downstream Products

• 573693-15-9 1,6-bis-(tert-butyl-diphenyl-silanyloxy)-8-(2,5-dimethyl-hex-1-enyl)-7-methyl-9H-carbazole-4-carboxylic acid methyl ester 
• 573693-16-0 [1,6-bis-(tert-butyl-diphenyl-silanyloxy)-8-(2,5-dimethyl-hex-1-enyl)-7-methyl-9H-carbazol-4-yl]-methanol 
• 573693-14-8 8-bromo-1,6-bis-(tert-butyl-diphenyl-silanyloxy)-7-methyl-9H-carbazole-4-carboxylic acid methyl ester 
• 886036-90-4 1,6-bis-(tert-butyl-diphenyl-silanyloxy)-8-(2,5-dimethyl-hept-1-enyl)-7-methyl-9H-carbazole-4-carboxylic acid methyl ester 
• 886036-91-5 [1,6-bis-(tert-butyl-diphenyl-silanyloxy)-8-(2,5-dimethyl-hept-1-enyl)-7-methyl-9H-carbazol-4-yl]-methanol 
• 573693-12-6 3-(2-bromo-4-methoxy-3-methyl-phenylamino)-4-methoxy-benzoic acid methyl ester 

Relevant academic research and scientific papers

First total synthesis of the neuronal cell protecting carbazole alkaloid carbazomadurin A by sequential transition metal-catalyzed reactions

The highly oxygenated neuronal cell protecting carbazole alkaloid carbazomadurin A was synthesized in nine steps and 11% overall yield from isovanillic acid.

1,3,4-OXADIAZOLONE COMPOUND AND MEDICINE

The purpose of the present invention is to provide a compound having PIM inhibitory activity. Examples of the present invention include 1,3,4-oxadiazolone compounds represented by the following formula [1], and pharmaceutically acceptable salts, and solvates thereof. The compounds of the present invention have PIM inhibitory activity. In addition, since the compounds of the present invention have PIM inhibitory activity, the compounds of the present invention are useful as therapeutic agents for systemic lupus erythematosus, lupus nephritis, etc.

NOVEL 1,2,3,4-TETRAHYDROQUINOXALINE DERIVATIVE HAVING GLUCOCORTICOID RECEPTOR BINDING ACTIVITY

An object of the present invention is to synthesize a novel 1,2,3,4-tetrahydroquinoxaline derivative represented by formula (1) and to find a pharmacological action of the derivative. In the formula, the R1 represents a halogen, an alkyl, cycloalkyl, aryl or heterocyclic group, or the like; p represents 0 to 5; R2 represents a halogen, an alkyl, hydroxyl or alkoxy group, or the like; q represents 0 to 2; R3 represents hydrogen, an alkyl, alkenyl, alkylcarbonyl or arylcarbonyl group, or the like; R4 and R5 independently represent hydrogen, a halogen, an alkyl, alkenyl, alkynyl, cycloalkyl, aryl or heterocyclic group, or the like; R6 represents hydrogen, an alkyl, alkenyl, alkynyl, cycloalkyl, aryl or heterocyclic group, or the like; A represents an alkylene; R7 represents OR8, NR8R9, SR8, S(O)R8, S(O)2R8; and X represents O or S.