57384-89-1

Basic information

• Product Name: 1-(3-fluoro-benzyl)-1H-benzo[d][1,3]oxazine-2,4-dione
• Synonyms: 1-(3-fluoro-benzyl)-1H-benzo[d][1,3]oxazine-2,4-dione
• CAS NO: 57384-89-1
• Molecular Weight: 271.248
• Mol File: 57384-89-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-(3-fluoro-benzyl)-1H-benzo[d][1,3]oxazine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-fluoro-benzyl)-1H-benzo[d][1,3]oxazine-2,4-dione(57384-89-1)
• EPA Substance Registry System: 1-(3-fluoro-benzyl)-1H-benzo[d][1,3]oxazine-2,4-dione(57384-89-1)

Safety Data

• Hazardous Substances Data: 57384-89-1(Hazardous Substances Data)

Upstream product

• 118-48-9 isatoic anhydride 
• 456-41-7 1-(Bromomethyl)-3-fluorobenzene 
• 456-47-3 3-fluoro-benzenemethanol 

Relevant articles and documents

Synthesis and antibiofilm evaluation of 3-hydroxy-2,3-dihydroquinazolin-4(1H)-one derivatives against opportunistic pathogen Acinetobacter baumannii

The emergence of multidrug resistant microorganisms has triggered the impending need for new aitimicrobial strategies. The antivirulence strategy with the benefite of alleviating the drug resistance becomes the focus of research. In this study, 22 quorum sensing inhibitors were synthesized by mimicking the structure of autoinducer and acinetobactin and up to 34% biofilm inhibition was observed with 5u. The biofilm inhibition effect was further demonstrated with extracellular polysaccharides inhibition and synergism with Gentamycin sulphate.

The chemistry of 2H 3,1 benzoxazine 2,4(1H)dione (isatoic anhydrides). I. The synthesis of N substituted 2H 3,1 benzoxazine 2,4(1H)diones

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