5739-10-6

Basic information

• Product Name: 2-IMIDAZOL-1-YL-ETHYLAMINE DIHYDROCHLORIDE
• Synonyms: 2-IMIDAZOL-1-YL-ETHYLAMINE DIHYDROCHLORIDE;1H-Imidazole-1-ethanamine;N-(2-Aminoethyl)imidazole;[2-(1H-imidazol-1-yl)ethyl]amine hydrochloride;2-(1H-Imidazol-1-yl)ethanamine;2-(1H-imidazol-1-yl)ethanamine(SALTDATA: 2HCl);2-(1H-iMidazol-1-yl)ethan-1-aMine dihydrochloride;2-Imidazol-1-yl-ethylamine1500
• CAS NO: 5739-10-6
• Molecular Formula: C₅H₉N₃
• Molecular Weight: 111.15
• Product Categories: Imidazol&Benzimidazole
• Mol File: 5739-10-6.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 283℃
• Flash Point: 125℃
• Appearance: /
• Density: 1.15
• Vapor Pressure: 0.003mmHg at 25°C
• Refractive Index: 1.577
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 7.51±0.10(Predicted)
• CAS DataBase Reference: 2-IMIDAZOL-1-YL-ETHYLAMINE DIHYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-IMIDAZOL-1-YL-ETHYLAMINE DIHYDROCHLORIDE(5739-10-6)
• EPA Substance Registry System: 2-IMIDAZOL-1-YL-ETHYLAMINE DIHYDROCHLORIDE(5739-10-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 5739-10-6(Hazardous Substances Data)

Usage

General Description

2-Imidazol-1-yl-ethylamine dihydrochloride is a chemical compound with the molecular formula C6H14Cl2N4. It is a dihydrochloride salt derivative of 2-imidazol-1-yl-ethylamine, which is a derivative of histamine. 2-IMIDAZOL-1-YL-ETHYLAMINE DIHYDROCHLORIDE is commonly used in the pharmaceutical industry as a precursor in the synthesis of various drugs, particularly those targeting the central nervous system and cardiovascular system. It is also used as a research tool in studies related to histamine receptors and their role in various physiological and pathological processes. Additionally, it has been investigated for its potential antifungal and antimicrobial properties, making it a versatile compound with multiple potential applications in research and drug development.

InChI:InChI=1/C5H9N3/c6-1-3-8-4-2-7-5-8/h2,4-5H,1,3,6H2

Upstream product

• 288-32-4 1H-imidazole 
• 140-88-5 ethyl acrylate 
• 18999-46-7 methyl 3-(imidazol-1-yl)propionate 
• 1190617-85-6 C₆H₁₀N₄O 
• 558441-67-1 (2-imidazol-1-yl-ethyl)-carbamic acid tert-butyl ester 
• 870-24-6 2-chloroethanamine hydrochloride 
• 72459-53-1 2-[2-(1H-imidazol-1-yl)ethyl]-isoindole-1,3(2H)-dione 

Downstream Products

• 260563-82-4 5-chloro-N-[2-(imidazol-1-yl)ethyl]-2,4-dinitrobenzamide 
• 393785-01-8 N-{N-[2-(imidazol-1-yl)ethyl]carbamoyl}-5(S)-3,9,10,11-tetramethoxy-6,7-dihydro-5H-dibenzo[a,c]cyclohepten-5-ylamine 
• 1011718-83-4 C₂₇H₃₂Cl₂N₄O₆S 
• 313681-27-5 (3R,3AS,6AR)-Hexahydrofuro[2,3-b]furan-3-yl (1S,2R)-3-[(1,3-benzodioxol-5-ylsulfonyl)(isobutyl)amino]-2-hydroxy-1-{4-[({[2-(1H-imidazol-1-yl)ethyl]amino}carbonyl)oxy]benzyl}propylcarbamate 

Relevant articles and documents

Rhein specific group modified organic compound, aryl metal complex, preparation method and application thereof

The invention discloses a rhein specific group modified organic compound, an aryl metal complex, a preparation method and application thereof. Compared with rhein molecules, the organic compound and metal complex have better antitumor and antibacterial activity, and the metal complex also can induce nucleic acid configuration transformation. Specifically, the aryl metal dimer and the above-mentioned metal complex both have good FTO (fat mass and obesity associated) inhibitory activity, and are good FTO inhibitors. The invention also discloses a synthesis method of the organic compound and themetal complex thereof, and the method has the characteristics of simple technological process, easy operation, and high yield. Finally, the invention discloses application of the rhein group-containing organic compound, the metal complex and aromatic metal dimer thereof in preparation of FTO inhibitor drugs, FTO inhibitor drug components, weight-reducing drugs, weight-reducing drug components, anticancer drugs, anticancer drug components, antibacterial drugs and antibacterial drug components.

Synthesis and characterization of N-substitutional ethylenediamine derivatives

N-Substituted and N,N-disubstituted ethylenediamine derivatives were prepared rapidly in aqueous conditions from 30 to 76 % yields, respectively, on a multi-gram scale starting from inexpensive and commercially available starting materials. The steps involved Michael addition, hydrazinolysis and Curtius rearrangements. The highlight of this method lies on its convenience and economy in accessing these intermediates.

CHEMICAL COMPOUNDS

The present invention provides novel compounds that demonstrate protective effects on target cells from HIV infection in a manner as to bind specifically to the chemokine receptor, and which affect the binding of the natural ligand or chemokine to a receptor such as CXCR4 and/or CCR5 of a target cell.