573982-45-3Relevant academic research and scientific papers
Discovery of a new binding mode for a series of liver X receptor agonists
Kopecky, David J.,Jiao, Xian Yun,Fisher, Ben,McKendry, Sharon,Labelle, Marc,Piper, Derek E.,Coward, Peter,Shiau, Andrew K.,Escaron, Patrick,Danao, Jean,Chai, Anne,Jaen, Juan,Kayser, Frank
, p. 2407 - 2410 (2012/05/05)
Structural modification of a series of dual LXRα/β agonists led to the identification of a new class of LXRβ partial agonists. An X-ray co-crystal structure shows that a representative member of this series, pyrrole 5, binds to LXRβ with a reversed orient
Arylsulfonamidobenzylic compounds
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Page 37 - 38, (2010/02/05)
Arylsulfonamidobenzyl alcohols, amines and sulfonamides are provided which are useful in treating lipid disorders, metabolic diseases and cell-proliferative diseases.
