72385-31-0Relevant academic research and scientific papers
Nanosized CdS as a Reusable Photocatalyst: The Study of Different Reaction Pathways between Tertiary Amines and Aryl Sulfonyl Chlorides through Visible-Light-Induced N-Dealkylation and C-H Activation Processes
Firoozi, Somayeh,Hosseini-Sarvari, Mona
, p. 2117 - 2134 (2021/02/05)
It has been found that the final products of the reaction of sulfonyl chlorides and tertiary amines in the presence of cadmium sulfide nanoparticles under visible light irradiation are highly dependent on the applied reaction conditions. Interestingly, with the change of a reaction condition, different pathways were conducted (visible-light-induced N-dealkylation or sp3 and sp2 C-H activation) that lead to different products such as secondary amines and various sulfonyl compounds. Remarkably, all of these reactions were performed under visible light irradiation and an air atmosphere without any additive or oxidant in benign solvents or under solvent-free conditions. During this study, the CdS nanoparticles as affordable, heterogeneous, and recyclable photocatalysts were designed, successfully synthesized, and fully characterized and applied for these protocols. During these studies, intermediates resulting from the oxidation of tertiary amines are trapped during the photoinduced electron transfer (PET) process. The reaction was carried out efficiently with a variety of substrates to give the corresponding products at relatively short times in good to excellent yields in parallel with the use of the visible light irradiation as a renewable energy source. Most of these processes are novel or are superior in terms of cost-effectiveness, safety, and simplicity to published reports.
Development of novel silanol-based human pregnane X receptor (PXR) agonists with improved receptor selectivity
Toyama, Hirozumi,Shirakawa, Hitoshi,Komai, Michio,Hashimoto, Yuichi,Fujii, Shinya
, p. 4493 - 4501 (2018/08/06)
Pregnane X receptor (PXR) is a ligand-dependent transcription factor that is considered to be a potential therapeutic target for multiple diseases. Herein, we report the development and structure-activity relationship studies of a new series of hPXR agoni
Heterocyclic arylsulfonamidobenzylic compounds
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, (2008/06/13)
Heterocyclic arylsulfonamidobenzylic compounds are provided which are useful in treating lipid disorders, metabolic disorders and cell-proliferative diseases.
Arylsulfonamidobenzylic compounds
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Page 37, (2010/02/05)
Arylsulfonamidobenzyl alcohols, amines and sulfonamides are provided which are useful in treating lipid disorders, metabolic diseases and cell-proliferative diseases.
Stereoselectivity in the Wittig Reaction of Aromatic Ketones: Origin of Preference for the Olefin Geometry
Takeuchi, Kumiko,Paschal, Jonathan W.,Loncharich, Richard J.
, p. 156 - 168 (2007/10/02)
Investigation of the stereoselectivity observed in the Wittig reaction of aromatic ketones with "nonstabilized" phosphonium ylides revealed that the nature of the substituent on the phenyl ring of phenyl 3-pyridyl ketone determined the stereoselectivity.G
