574008-40-5

Basic information

• Product Name: 1(2H)-Phthalazinone, 4-[5-(phenylmethoxy)pentyl]-
• CAS NO: 574008-40-5
• Molecular Formula: C20H22N2O2
• Molecular Weight: 322.407
• Mol File: 574008-40-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1(2H)-Phthalazinone, 4-[5-(phenylmethoxy)pentyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1(2H)-Phthalazinone, 4-[5-(phenylmethoxy)pentyl]-(574008-40-5)
• EPA Substance Registry System: 1(2H)-Phthalazinone, 4-[5-(phenylmethoxy)pentyl]-(574008-40-5)

Safety Data

• Hazardous Substances Data: 574008-40-5(Hazardous Substances Data)

Upstream product

• 78999-24-3 5-benzyloxy-1-pentanal 
• 42116-86-9 (3-oxo-1,3-dihydro-2-benzofuran-1-yl)(triphenyl)phosphonium bromide 

Relevant articles and documents

4-Phenyl-1,2,3,6-tetrahydropyridine, an excellent fragment to improve the potency of PARP-1 inhibitors

We have shown that a 4-phenyl-1,2,3,6-tetrahydropyridine fragment plays an important role in improving inhibitory potency against poly(ADP-ribose) polymerase-1 (PARP-1). Various benzamide analogues linked with this fragment via alkyl spacers have been prepared and evaluated. As a result, some of them have been found to be highly potent PARP-1 inhibitors.