57435-35-5Relevant academic research and scientific papers
Asymmetric conjugate additions to 1,1′-diactivated cyclic enones-a comparative study
Tang, Xiaoping,Blake, Alexander J.,Lewis, William,Woodward, Simon
experimental part, p. 1881 - 1891 (2010/02/27)
A study of copper-phosphoramidite-catalysed ZnR2 and AlR3 additions to 1,1′-dicarbonyl-activated cyclic Michael acceptors has revealed high enantioselectivities for AlR3 (R = Me, Et) 1,4-addition to a range of 3-acylcoumarins (85-98% ee, trans:cis ～90:10) using commercial or readily available ligands. Large substituents at the 6-position, and to some extent at the 5-position, of the coumarin are less well tolerated, nor is truncation of the coumarin motif to a comparable 2-acylcyclohexenone (ee values up to 78%).
Snythesis of 3-Styrylcoumarins from Coumarin-3-acetic Acids and 3-Phenacylcoumarins
Chodankar, N. K.,Joshi, S. D.,Sequeria, S.,Seshadri, S.
, p. 427 - 430 (2007/10/02)
The hitherto unknown 3-styrylcoumarin system has been synthesised by two routes.In the first approach, coumarin-3-acetic acids are reacted with aromatic aldehydes to yield directly the 3-styrylcoumarins.The synthesis is limited by the difficulty in obtaining coumarin-3-acetic acids in good yields.The second approach utilises 3-phenacylcoumarins which are reduced to the carbinols and subsequently dehydrated to the corresponding 3-styrylcoumarins.The fluorescence of these compounds and their application to polyester fibre have been studied.
