113231-48-4

Upstream product

• 20862-58-2 2-(2-oxo-2H-chromen-3-yl)acetic acid 
• 100-52-7 benzaldehyde 
• 2051-95-8 succinylbenzene 
• 91-64-5 coumarin 
• 621-82-9 Cinnamic acid 
• 90-02-8 salicylaldehyde 
• 113231-71-3 3-(1-Hydroxy-2-phenyl-ethyl)-chromen-2-one 
• 57435-35-5 3-(2-phenylacetyl)-2H-chromen-2-one 
• 16281-76-8 3-[1-(2-Hydroxy-phenyl)-meth-(Z)-ylidene]-5-phenyl-3H-furan-2-one 

Relevant academic research and scientific papers

Regioselective palladium-catalyzed decarboxylative cross-coupling reaction of alkenyl acids with coumarins: Synthesis of 3-styrylcoumarin compounds

A novel and efficient protocol for the regioselective synthesis of 3-styrylcoumarins from readily available cinnamic acids and coumarins is presented. The reaction proceeds via a decarboxylative cross-coupling mediated by a catalytic amount of Pd(OAc)2, with Ag2CO3 as an oxidant, and with 1,10-phenanthroline as a ligand. A plausible reaction mechanism for this process is depicted, and the resulting 3-styrylcoumarins show excellent fluorescence quantum yields.

Snythesis of 3-Styrylcoumarins from Coumarin-3-acetic Acids and 3-Phenacylcoumarins

The hitherto unknown 3-styrylcoumarin system has been synthesised by two routes.In the first approach, coumarin-3-acetic acids are reacted with aromatic aldehydes to yield directly the 3-styrylcoumarins.The synthesis is limited by the difficulty in obtaining coumarin-3-acetic acids in good yields.The second approach utilises 3-phenacylcoumarins which are reduced to the carbinols and subsequently dehydrated to the corresponding 3-styrylcoumarins.The fluorescence of these compounds and their application to polyester fibre have been studied.