57440-79-6 Usage
Chemical compound
1-pyrenebutyrylcholine (PBCH) is a chemical compound.
Family
It belongs to the family of pyrene analogues.
Structure
PBCH consists of a pyrene group, a butyryl group, and a choline molecule.
Use
It is used as a substrate for studies related to acetylcholinesterase activity.
Field of use
PBCH is used in the field of neuroscience and pharmacology.
Function
It is commonly used in fluorescence assays to measure the hydrolysis of acetylcholine by acetylcholinesterase.
Purpose
PBCH provides valuable insights into the mechanism of enzyme activity and the development of potential inhibitors.
Importance
It is a useful tool in research and is crucial for understanding the role of acetylcholinesterase in various physiological and pathological processes.
Check Digit Verification of cas no
The CAS Registry Mumber 57440-79-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,4,4 and 0 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 57440-79:
(7*5)+(6*7)+(5*4)+(4*4)+(3*0)+(2*7)+(1*9)=136
136 % 10 = 6
So 57440-79-6 is a valid CAS Registry Number.
InChI:InChI=1/C25H28NO2.BrH/c1-26(2,3)16-17-28-23(27)9-5-6-18-10-11-21-13-12-19-7-4-8-20-14-15-22(18)25(21)24(19)20;/h4,7-8,10-15H,5-6,9,16-17H2,1-3H3;1H/q+1;/p-1
57440-79-6Relevant academic research and scientific papers
Chen, Jian,Liao, Dongli,Wang, Yan,Zhou, Huipeng,Li, Wenying,Yu, Cong
, p. 2132 - 2135 (2013)
A choline labeled pyrene probe (Py-Ch) was designed and synthesized. Poly(vinylsulfonate) (PVS) could induce Py-Ch aggregation. The aggregation and deaggregation process could be finely controlled by the acetylcholinesterase (AChE) enzymatic hydrolysis of Py-Ch. The resulting excimer-monomer transition provided a facile way for real-time AChE activity fluorometric assay and inhibitor screening.
