57465-49-3Relevant academic research and scientific papers
Rhodium-Catalyzed Reaction of Silacyclobutanes with Unactivated Alkynes to Afford Silacyclohexenes
Chen, Hua,Chen, Yi,Tang, Xiaoxiao,Liu, Shunfa,Wang, Runping,Hu, Tianbao,Gao, Lu,Song, Zhenlei
supporting information, p. 4695 - 4699 (2019/03/07)
A Rh-catalyzed reaction of silacyclobutanes (SCBs) with unactivated alkynes has been developed to form silacyclohexenes with high chemoselectivity. Good enantioselectivity at the stereogenic silicon center was achieved using a chiral phosphoramidite ligand. The resulting silacyclohexenes are useful scaffolds for synthesizing structurally attractive silacyclic compounds.
Palladium-catalyzed desymmetrization of silacyclobutanes with alkynes: Enantioselective synthesis of silicon-stereogenic 1-sila-2-cyclohexenes and mechanistic considerations
Shintani, Ryo,Moriya, Kohei,Hayashi, Tamio
, p. 2902 - 2905 (2012/07/17)
A palladium-catalyzed enantioselective desymmetrization of silacyclobutanes with alkynes has been developed to give silicon-stereogenic 1-sila-2-cyclohexenes with high enantioselectivity. The products thus obtained undergo further derivatizations with complete stereoselectivity, and a new catalytic cycle involving alkyne coordination (oxidative cyclization)- transmetalation (σ-bond metathesis)-reductive elimination has also been proposed.
