57488-14-9Relevant academic research and scientific papers
A Mild Hydroaminoalkylation of Conjugated Dienes Using a Unified Cobalt and Photoredox Catalytic System
Thullen, Scott M.,Rovis, Tomislav
, p. 15504 - 15508 (2017)
Metallo-photoredox catalysis has redefined the available bond disconnections in the synthetic arsenal. By harnessing the one-electron chemistry of photoredox catalysis in tandem with low-valent cobalt catalysts, new methods by which functionalities may be stitched together become available. Herein we describe the coupling of photoredox-generated α-amino radical species with conjugated dienes using a unified cobalt and iridium catalytic system in order to access a variety of useful homoallylic amines from simple commercially available starting materials. We present a series of mechanistic experiments that support the intervention of Co-hydride intermediates that undergo diene insertion to generate Co-π-allyl species.
Alkylation of the α-amino C-H bonds of anilines photocatalyzed by a DMEDA-Cu-benzophenone complex: reaction scope and mechanistic studies
Abadie, Baptiste,Jonusauskas, Gediminas,McClenaghan, Nathan D.,Toullec, Patrick Y.,Vincent, Jean-Marc
supporting information, p. 5800 - 5805 (2021/07/12)
The Cu(ii) complex1incorporating a BP chromophore is a highly active and chemoselective photocatalyst for the alkylation of α-amino C-H bonds of anilines. The reaction was shown to proceed with a broad substrate scope in the absence of additives. Extensive mechanistic studies were performed, in particular using transient absorption spectroscopy, and spectroscopic signatures of key intermediates were identified in the conditions of catalysis. Finally, the ability of1to act as a multitask catalyst was showcased by conducting multi-component CuAAC and olefin hydroalkylation reactions in one-pot.
Synthesis method of photocatalytic tertiary amine compound
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Paragraph 0116-0119, (2020/03/06)
The invention discloses a synthesis method of a photocatalytic tertiary amine compound. The method is specifically carried out according to the steps of: adding a photosensitizer and an alkaline substance into a Schlenk reaction tube, in a nitrogen atmosp
Anti-hypertensive 5-[2-(substituted anilinoalkylamino)-1-hydroxyalkyl]salicylamides
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, (2008/06/13)
5-[2-(Substituted-anilinoalkylamino)-1-hydroxyalkyl]-salicylamides, particularly useful as agents for the treatment of hypertension, are disclosed herein.
