57545-46-7Relevant academic research and scientific papers
Total Synthesis and Anticancer Activity of (+)-Hypercalin C and Congeners
Tao, Yongfeng,Reisenauer, Keighley,Taube, Joseph H.,Romo, Daniel
, p. 2734 - 2738 (2019)
The hypercalins are dearomatized acylphloroglucinols with a pendant complex cyclopentane ring that exhibit activity against several cancer cell lines. We report the first total synthesis of (+)-hypercalin C employing a convergent strategy that enabled the
An unexpected acid mediated rearrangement of monoethylene ketal of 2-methyl-2-(3-methylbut-2-en-1-yl)cyclohex-4-ene-1,3-diones to chromane
Sreenivas, Kukkamudi,Khan, Faiz Ahmed
, p. 1244 - 1248 (2018)
We herein report a serendipitously observed acid mediated rearrangement of monoethylene ketal of 2-methyl-2-(3-methylbut-2-en-1-yl)cyclohex-4-ene-1,3-diones to Dihydrobenzopyran and demonstrated the application of this methodology in the construction of core carbon scaffolds of dimethoxyajacareubin, cariphenone-A and crotamadine.
New chemical access for pyran core embedded derivatives from bisalkenylated 1,3-diketones and 1,3-diketoesters via tandem C-dealkenylation and cyclization
Narender,Sarkar,Venkateswarlu,Kumar
experimental part, p. 6576 - 6579 (2011/02/24)
New chemical access has been developed for the synthesis of pyran core embedded derivatives from 1,3diketones and 1,3-diketoesters, in which the active methylene group of 1,3-diketone or 1,3-diketoester was alkenylated with three equivalents of alkenyl br
