57585-09-8

Upstream product

• 492-37-5 hydratropic acid 
• 25145-43-1 2-phenylpropionyl chloride 
• 186581-53-3 diazomethane 
• 57585-21-4 (aS)-4-methyl-4-phenyl-2,3-allenoic acid 
• 5927-18-4 trimethyl phosphonoacetate 
• 681123-85-3 methyl methyl(2,2,2-trifluoroethyl)phosphonoacetate 
• 88738-78-7 bis-(2,2,2-trifluoroethyl)(methoxycarbonylmethyl)phosphonate 
• 55442-34-7 3,3'-dimethyl-1,1'-binaphthalene-2,2'-diol 
• 179042-34-3 (2,6-Dimethyl-4-oxo-3,5-dioxa-4λ⁵-phospha-cyclohepta[2,1-a;3,4-a']dinaphthalen-4-yl)-acetic acid methyl ester 
• 57585-21-4 4-phenylpenta-2,3-dienoic acid 

Downstream Products

• 52161-56-5 4-phenyl-pent-3-enoic acid methyl ester 
• 64252-49-9 (E)-4-Phenyl-2-pentensaeure-methylester 

Relevant academic research and scientific papers

Enantioselective preparation of allenecarboxylates by asymmetric Horner-Wadsworth-Emmons reaction

Optically active 4,4-disubstituted conjugated allenecarboxylates were enantioselectively prepared via C=C bond formation through an asymmetric Horner-Wadsworth-Emmons reaction with an optically active phosphonoacetate reagent.

Synthesis of Allenyl Esters by Horner-Wadsworth-Emmons Reactions of Ketenes Mediated by Isopropylmagnesium Bromide

The synthesis of conjugated allenyl esters (tri-substituted allenes) was achieved by magnesium(II)-mediated Horner-Wadsworth-Emmons reaction of methyl bis(2,2,2-trifluoroethyl)phosphonoacetate with disubstituted ketenes. In addition, a novel access to α-fluorinated allenyl carboxamides (tetrasubstituted allenes) is presented.

Biotransformations of racemic 2,3-allenenitriles in biphasic systems: Synthesis and transformations of enantioenriched axially chiral 2,3-allenoic acids and their derivatives

Catalyzed by Rhodococcus erythropolis AJ270 whole cells in an aqueous phosphate buffer-n-hexane biphasic system, racemic axially chiral 2,3-allenenitriles underwent hydrolysis to afford enantioenriched (aR)-2,3-allenamides and (aS)-2,3-allenoic acids with