57598-88-6

Basic information

• Product Name: METHYL 3-HYDROXYQUINUCLIDINE-3-CARBOXYLATE
• Synonyms: METHYL 3-HYDROXYQUINUCLIDINE-3-CARBOXYLATE;3-Hydroxy-1-aza-bicyclo[2.2.2]octane-3-carboxylic acid methyl ester
• CAS NO: 57598-88-6
• Molecular Formula: C₉H₁₅NO₃
• Molecular Weight: 185.22
• Mol File: 57598-88-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: METHYL 3-HYDROXYQUINUCLIDINE-3-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 3-HYDROXYQUINUCLIDINE-3-CARBOXYLATE(57598-88-6)
• EPA Substance Registry System: METHYL 3-HYDROXYQUINUCLIDINE-3-CARBOXYLATE(57598-88-6)

Safety Data

• Hazardous Substances Data: 57598-88-6(Hazardous Substances Data)

Upstream product

• 6238-30-8 3-hydroxy-1-azabicyclo[2.2.2]octane-3-carbonitrile 

Downstream Products

• 107869-78-3 2'(R)-methylspiro<1-azabicyclo<2.2.2>octane-3(S),4'-<1,3>dioxolane> 
• 98593-29-4 1-aza-bicyclo[2.2.2]oct-2-ene-3-carboxylic acid 
• 33630-87-4 1-aza-bicyclo[2.2.2]oct-2-ene-3-carboxylic acid methyl ester; hydrochloride 
• 31539-88-5 methyl 1-azabicyclo(2,2,2)oct-2-ene-3-carboxylate 

Relevant articles and documents

Imidazole derivatives and salts thereof and pharmaceutical formulations useful in thrombo-embolic disorders

Imidazoles of formula (I) STR1 wherein A is a chemical bond or a straight or branched, saturated or unsaturated, aliphatic residue having from 1 to 6 carbon atoms wherein 1, 2 or 3 of such carbon atoms may be replaced by a corresponding number of heteroatoms selected from oxygen, sulphur and nitrogen providing (in the case of 2 or 3 heteroatoms) that any such heteroatom is not located adjacent to a further such heteroatoms or heteroatoms R is a fused, saturated or unsaturated, non-aromatic carbocyclic, polycyclic ring system; a saturated or unsaturated, carbocyclic spirocyclic ring system, optionally containing one or more ring heteroatoms selected from oxygen, sulphur and nitrogen; or a saturated or unsaturated, carbocyclic bridged-polycyclic ring system, optionally containing one or more ring heteroatoms selected from oxygen, sulphur and nitrogen and having one or more bridges; or AR together represent a straight or branched, saturated or unsaturated, aliphatic residue having 3 to 6 carbon atoms, wherein 1, 2 or 3 of such carbon atoms may be replaced by a corresponding number of heteroatoms selected from oxygen, sulphur and nitrogen providing (in the case of 2 or 3 heteroatoms) that any such heteroatom is not located adjacent to a further such heteroatom or heteroatoms; which aliphatic residue is substituted by at least two groups, which may be the same or different, selected from the groups specified for R above. and acid addition salts and pharmaceutically acceptable bioprecursors thereof. Methods of preparing the imidazoles are disclosed. The imidazoles and their acid addition salts and bioprecursors are useful in the treatment or prophylaxis of thrombo-embolic conditions.