57615-66-4

Upstream product

• 620-79-1 Ethyl 2-benzylacetoacetate 
• 61013-61-4 ethyl 2-azido-3-phenylacrylate 
• 252054-88-9 1-(trimethylsilyl)naphthalen-2-yl triflate 

Downstream Products

• 138653-64-2 1-Cyanomethyl-3-phenyl-1H-benzo[g]indole-2-carboxylic acid ethyl ester 
• 105492-15-7 3-Phenyl-1H-benzo[g]indole-2-carboxylic acid hydrazide 
• 138654-01-0 1-Carboxymethyl-3-phenyl-1H-benzo[g]indole-2-carboxylic acid 
• 138653-73-3 7-Phenyl-8,9,10,11-tetrahydro-9,11a-diaza-benzo[c]fluorene 
• 139389-04-1 1-(2-Amino-ethyl)-3-phenyl-1H-benzo[g]indole-2-carboxylic acid ethyl ester 
• 105492-23-7 (3-Phenyl-1H-benzo[g]indol-2-yl)-carbamic acid ethyl ester 
• 105492-19-1 3-Phenyl-1H-benzo[g]indole-2-carbonyl azide 
• 105492-28-2 C₁₉H₁₆N₄O 

Relevant academic research and scientific papers

Synthesis of substituted indoles from 2-azidoacrylates and ortho-silyl aryltriflates

2-Azidoacrylates react with benzynes in the presence of PPh3 and CsF to afford substituted indoles in good yields. The reaction involves the formation of iminophosphorane and benzyne and a subsequent double cyclization/hydrolysis/air-oxidation cascade. This methodology was utilized to synthesize 10H-indolo[1,2-a]indol-10-ones.