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Benclonidine is a centrally-acting alpha-agonist hypotensive agent that is primarily used for the management of hypertension. It works by stimulating alpha-adrenergic receptors in the central nervous system, leading to a decrease in sympathetic outflow and resulting in vasodilation and a reduction in blood pressure. Benclonidine has also been investigated for its potential use in treating opioid withdrawal symptoms and attention-deficit hyperactivity disorder (ADHD), although its use in these conditions is not as well-established as its use in hypertension. It is a promising therapeutic agent with a wide range of potential applications in the field of medicine.

57647-79-7

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57647-79-7 Usage

Uses

Used in Pharmaceutical Industry:
Benclonidine is used as an antihypertensive agent for the management of hypertension, a condition characterized by high blood pressure. It helps in reducing blood pressure by stimulating alpha-adrenergic receptors in the central nervous system, leading to a decrease in sympathetic outflow and resulting in vasodilation.
Used in Opioid Withdrawal Treatment:
Benclonidine is used as a potential treatment for opioid withdrawal symptoms. It has been investigated for its ability to alleviate the symptoms associated with opioid withdrawal, although its use in this condition is not as well-established as its use in hypertension.
Used in Attention-Deficit Hyperactivity Disorder (ADHD) Treatment:
Benclonidine is used as a potential treatment for attention-deficit hyperactivity disorder (ADHD). It has been studied for its potential to improve symptoms associated with ADHD, such as inattention, hyperactivity, and impulsivity. However, its use in this condition is not as well-established as its use in hypertension.

Check Digit Verification of cas no

The CAS Registry Mumber 57647-79-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,6,4 and 7 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 57647-79:
(7*5)+(6*7)+(5*6)+(4*4)+(3*7)+(2*7)+(1*9)=167
167 % 10 = 7
So 57647-79-7 is a valid CAS Registry Number.
InChI:InChI=1/C16H13Cl2N3O/c17-12-7-4-8-13(18)14(12)20-16-19-9-10-21(16)15(22)11-5-2-1-3-6-11/h1-8H,9-10H2,(H,19,20)

57647-79-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name [2-(2,6-dichloroanilino)-4,5-dihydroimidazol-1-yl]-phenylmethanone

1.2 Other means of identification

Product number -
Other names 1-benzoyl-2-(2,6-dichloro-anilino)-4,5-dihydro-1H-imidazole

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:57647-79-7 SDS

57647-79-7Downstream Products

57647-79-7Relevant academic research and scientific papers

Feed additive for improving growth in agricultural animals

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, (2008/06/13)

By using α-mimetics, particularly compounds of general formulae I to III and the compounds listed in Table I, as feed additives in fattening animals, it has surprisingly been possible to improve the daily weight gain, the utilisation of fodder and the ratio of muscle to fat in favor of the proportion of muscle and protein.

Imidazoline derivatives and the preparation thereof

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, (2008/06/13)

A process for the preparation of 2-(substituted aryl)amino-2-imidazoline derivatives by reacting appropriate substituted aniline derivatives with 1-aroyl-imidazoline-2-ones in the presence of at least two mols of phosphorus oxychloride per mol of the aniline derivative and optionally hydrolyzing the resulting intermediate compound. Certain novel 2-dihaloarylamino-2-imidazoline derivatives with hypotensive action are also disclosed.

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