57662-47-2 Usage
General Description
3-(3-methyl-1H-indol-1-yl)propanoic acid, also known as melatonin, is a hormone and antioxidant produced by the body in response to darkness. It regulates the sleep-wake cycle and has been used as a dietary supplement to treat sleep disorders, jet lag, and insomnia. As a chemical, it is a derivative of the amino acid tryptophan and functions as a neurotransmitter in the brain. It has also been studied for its potential role in mediating various physiological functions, including mood regulation, immunity, and aging. Additionally, melatonin has been investigated for its potential as a treatment for certain neurodegenerative diseases and cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 57662-47-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,6,6 and 2 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 57662-47:
(7*5)+(6*7)+(5*6)+(4*6)+(3*2)+(2*4)+(1*7)=152
152 % 10 = 2
So 57662-47-2 is a valid CAS Registry Number.
InChI:InChI=1/C12H13NO2/c1-9-8-13(7-6-12(14)15)11-5-3-2-4-10(9)11/h2-5,8H,6-7H2,1H3,(H,14,15)
57662-47-2Relevant articles and documents
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Hoechst,Roeder
, p. 779,782 (1975)
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269. Intramolecular Carbenoid Reaction of Pyrrole Derivatives. Efficient Syntheses of Pyrrolizinone and Dihydroindolizinone
Jefford, Charles W.,Johncock, William
, p. 2666 - 2671 (2007/10/02)
The copper-catalyzed pyrolysis of 1-diazo-3-(pyrrol-1-yl)-2-propanone (1a) and 1-diazo-4-(pyrrol-1-yl)-2-butanone (1b) in benzene solution gave 1H-pyrrolizin-2-(3H)-one (4a) and 5,6-dihydroindolizin-7(8H)-one (4b), respectively, in quantative yield.Similar pyrolysis of 1-diazo-4-(3-methylindol-1-yl)-2-butanone (9) was less efficient giving 1-methylbenzo-5,6-dihydroindolizin-7(8H)-one (10) and 4-(3-methylindol-1-yl)-but-1-en-3-one (11) in 7percent and 24percent yield, respectively.
