57681-56-8Relevant academic research and scientific papers
Pyridine-Substituted Hydroxythiophenes. III. Dimerization of 3-(2-Pyridyl)thiophen-2(5H)-one from the Demethylation Reaction of 2-Methoxy-3-(2-pyridyl)thiophene. X-Ray Structure Determination of (+-)-(3R*,4S*)-3-(2-Pyridyl)-4-<2-oxo-3-(1,2-dihydropyridin-2-ylidene)-2,3-dihydrothiophen...
Zhang, Yihua,Hoernfeldt, Anna-Britta,Gronowitz, Salo,Stalhandske, Claes
, p. 843 - 849 (2007/10/02)
The demethylation of 2-methoxy-3-(2-pyridyl)thiophene with chlrotrimethylsilane-sodium iodide in refluxing acetonitrile or with boron tribromide in dichloromethane at ambient temperature led to the formation of (+/-)-(3R*, 4S*)-3-(2-pyridyl)-4--4,5-dihydrothiophen-2(3H)-one.A possible mechanism by which the compound is formed is proposed.The structure of the compound has been established by X-ray crystallography.
