5770-49-0

Usage

InChI:InChI=1/C13H15N3O2/c1-15-11(8-12(17)16(2)13(15)18)14-9-10-6-4-3-5-7-10/h3-8,14H,9H2,1-2H3

Upstream product

• 6642-31-5 6-Amino-1,3-dimethylbarbituric acid 
• 100-51-6 benzyl alcohol 
• 6972-27-6 1,3-Dimethyl-6-chlorouracil 
• 100-46-9 benzylamine 
• 29601-98-7 N-benzylhydroxylamine hydrochloride 

Downstream Products

• 109507-50-8 6-benzylamino-5-bromo-1,3-dimethyl-1H-pyrimidine-2,4-dione 
• 932726-19-7 6-benzylamino-5-[3-(4-bromophenyl)-3-oxopropyl]-1,3-dimethyluracil 
• 1448800-39-2 6-(benzylamino)-1,3-dimethyl-5-(trifluoroacetyl)pyrimidine-2,4(1H,3H)-dione 
• 1448800-57-4 6,8-dimethyl-2-phenyl-4-(trifluoromethyl)-4,8-dihydro-2H-pyrimido[4,5-d][1,3]oxazine-5,7(1H,6H)-dione 
• 1257251-84-5 7'-benzyl-1',3'-dimethyl-3H-spiro[isobenzofuran-1,6'-pyrrolo[2,3-d]pyrimidine]-2',3,4',5'(1'H,3'H,7'H)-tetraone 
• 961-45-5 1,3-dimethyl-8-phenylxanthine 
• 105159-32-8 4-methyl-N-(2-phenyl-2-(phenylamino)ethyl)benzenesulfonamide 
• 105205-04-7 N-{2-[4-(6-Benzylamino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-ylmethyl)-phenylamino]-2-phenyl-ethyl}-4-methyl-benzenesulfonamide 
• 105159-23-7 6-Benzylamino-1,3-dimethyl-5-{4-[5-phenyl-3-(toluene-4-sulfonyl)-imidazolidin-1-yl]-benzyl}-1H-pyrimidine-2,4-dione 
• 89367-55-5 C₂₇H₃₀N₆O₄ 
• 21544-68-3 4,6-dimethyl-2-phenyl-4H-thiazolo[4,5-d]pyrimidine-5,7-dione 

Relevant academic research and scientific papers

Selective N-Monoalkylation of 6-Aminouracils with Alcohols: An Environmentally Benign Protocol for the Synthesis of 6-Alkylaminouracils

A highly selective N-alkylation of 6-aminouracils with alcohols was achieved through the borrowing hydrogen approach using iridium catalysis. 6-Aminouracils and alcohols reacted in the presence of [Cp*IrI2]2 to give 6-monoalkyluracils selectively and in high yield (up to 99 %), usually in short reaction times (2 h). These results provide a new, green, and efficient protocol for the synthesis of 6-alkylaminouracils, which are very important intermediates for the synthesis of biologically active molecules.

Synthesis and reactivity of 5-polyfluoroalkyl-5-deazaalloxazines

Reaction of 6-arylamino-1,3-dialkyluracils with anhydrides of polyfluorocarboxylic acids in the presence of pyridine and subsequent cyclization with concentrated H2SO4 gave the corresponding 1,3-dialkyl-5-(polyfluoroalkyl)pyrimido[4,

Two-step synthetic approach to 6-substituted pyrido[2,3-d]pyrimidine(1H,3H) -2,4-diones from 6-amino-, 6-alkylamino-, and 6-arylamino-1,3-dimethyluracils

The Mannich reaction of 7-aryl-5,6-dihydropyrido[2,3-d]pyrimidines 3, easily accessible by condensation of 6-amino-1,3-dimethyluracil (1) with Mannich bases 2a-c, gives rise to a mixture of 7-aryl-6-(N,N-dimethylaminomethyl) pyrido[2,3-d]pyrimidines 6 and

Synthesis of substituted uracils by the reactions of halouracils with selenium, sulfur, oxygen and nitrogen nucleophiles under focused microwave irradiation

Under microwave irradiation, the nucleophilic substitution reactions of halouracils with selenium, sulfur, oxygen and nitrogen nucleophiles was complete within several minutes with yields up to 99%. The method using microwave irradiation is superior to th

3,3-Sigmatropic rearrangements involving N-O bond-cleavage of enehydroxylamine derivatives

Enehydroxylamines, derived from carbocyclic and heterocyclic 1,3-dioxo compounds, react with a variety of unsaturated electrophiles to give, in good to excellent yields, substances that in general undergo 3,3-sigmatropic rearrangements either spontaneously or upon heating. In those cases in which such reactions failed, addition of sodium hydride was found to induce the transformation. A study of the rearrangement by use of deuterium-labelled compounds showed that no crossover occurs, indicating the intramolecular nature of the process. The method provides 2,3- or 3,4-disubstituted cyclohexenones, 5,6-disubstituted barbiturates and the corresponding fused pyrrole and imidazolinone derivatives. Wiley-VCH Verlag GmbH & Co KGAA, 69451 Weinheim, Germany, 2003.