105159-32-8

Upstream product

• 6642-31-5 6-Amino-1,3-dimethylbarbituric acid 
• 97511-33-6 3,4-diphenyl-1-tosylimidazolidine 
• 5770-42-3 1,3-dimethyl-6-methylamino-1H-pyrimidine-2,4-dione 
• 42164-54-5 N-(2-amino-1-phenylethyl)benzenamine 
• 98-59-9 p-toluenesulfonyl chloride 
• 24395-14-0 N-(p-tolylsulfonyl)-2-phenylaziridine 
• 62-53-3 aniline 
• 21080-09-1 NSC 4573 
• 100-42-5 styrene 
• 127-65-1 chloroamine-T 
• 55962-05-5 [N-(p-tolylsulfonyl)imino]phenyliodinane 
• 5770-49-0 6-(benzylamino)-1,3-dimethyluracil 
• 7278-51-5 6-anilino-1,3-dimethyluracil 

Downstream Products

• 97511-33-6 3,4-diphenyl-1-tosylimidazolidine 
• 97511-34-7 4-methyl-N-(2-(methyl(phenyl)amino)-2-phenylethyl)benzenesulfonamide 
• 105167-93-9 C₂₅H₂₆N₆O₄ 
• 105159-25-9 N-{2-[4-(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-ylmethyl)-phenylamino]-2-phenyl-ethyl}-4-methyl-benzenesulfonamide 
• 105159-28-2 N-{2-[4-(1,3-Dimethyl-2,4-dioxo-6-phenylamino-1,2,3,4-tetrahydro-pyrimidin-5-ylmethyl)-phenylamino]-2-phenyl-ethyl}-4-methyl-benzenesulfonamide 
• 105159-20-4 C₄₃H₄₄N₄O₄S₂ 
• 611232-63-4 N-(2-(benzyl(phenyl)amino)-2-phenylethyl)-4-methylbenzenesulfonamide 

Relevant academic research and scientific papers

LiClO4-catalyzed ring-opening of aziridines with aromatic amines

A variety of N-tosylaziridines undergo smoothly ring opening with aromatic amines using a catalytic amount of lithium perchlorate in acetonitrile at ambient temperature to afford the corresponding 1,2-diamines in excellent yields.

Indium tribromide catalyzed aminolysis of aziridines: An efficient synthesis of vicinal-diamines

Indium tribromide catalyzes efficiently the aminolysis of activated aziridines with aromatic amines under mild reaction conditions to afford the corresponding vicinal-diamines in high yields with high selectivity.

A highly efficient and general method for the ring-opening of aziridines with various nucleophiles in DMSO

Ring-opening of aziridines with various nucleophiles (such as amines, thiols, and silylated nucleophiles) in DMSO under mild conditions without any catalyst afforded the corresponding products in good to excellent yields. The Royal Society of Chemistry 20

Tantalum (V) chloride catalyzed ring opening of aziridines with aromatic amines

Tantalum (V) Chloride adsorbed on silicagel has been utilized as an efficient catalyst for ring opening of aziridines with aromatic amines for the synthesis of 1,2-diamines. Mild reaction conditions, high yields, operational simplicity, relatively less am

Ring-opening reaction of aziridines with amines under the influence of dimethyl sulfoxide to dedicated to late Tomoko Kakinuma, past member in our laboratory

The ring-opening reaction of various aziridines with amines proceeded at room temperature to afford the corresponding 1,2-diamines in good to excellent yields using only 3-5 equiv dimethyl sulfoxide (DMSO) to aziridines in hexane. This reaction can be performed with easy handling and proceeds under mild reaction conditions. Also a variety of amines are available as a nucleophile.

DABCO: An efficient organocatalyst in the ring-opening reactions of aziridines with amines or thiols

Efficient ring-opening of aziridines with various amines or thiols catalyzed by DABCO afforded the corresponding products in good to excellent yields under mild reaction conditions. Wiley-VCH Verlag GmbH & Co. KGaA, 2005.

1-Butyl-3-methylimidazolium Tetrafluoroborate ([Bmim]BF4) Ionic Liquid: A Novel and Recyclable Reaction Medium for the Synthesis of vic-Diamines

Aziridines undergo ring opening smoothly with various arylamines in 1-butyl-3-methylimidazolium tetrafluoroborate ([bmim]BF4) or 1-butyl-3-methylimidazolium hexafluorophosphate ([bmim]PF6) ionic liquids under mild and neutral conditi

HKUST-1 Metal Organic Framework as an Efficient Dual-Function Catalyst: Aziridination and One-Pot Ring-Opening Transformation for Formation of β-Aryl Sulfonamides with C-C, C-N, C-S, and C-O Bonds

Metal-organic frameworks (MOFs) are extensively used in catalysis due to their robust structure, well-defined periodic reaction centers, and high porosity. We report Cu3(BTC)2·(H2O)3 (HKUST-1) as an efficient heterogeneous catalyst for aziridination of al

Stereoselective Syntheses of Highly Functionalized Imidazolidines and Oxazolidines via Ring-Opening Cyclization of Activated Aziridines and Epoxides with Amines and Aldehydes

A mild one-pot stereospecific synthetic route to highly functionalized imidazolidines and oxazolidines via SN2-type ring-opening of the corresponding activated aziridines and epoxides with amines followed by p-toluenesulfonic acid (PTSA)-catalyzed intramolecular cyclization with aldehydes has been developed. The methodology tolerates a variety of functional groups and furnishes the desired products in high yields (up to 92%) with excellent stereoselectivities (de, ee > 99%). Interestingly, imidazolidines were formed as the cis-isomers, whereas oxazolidines were produced as trans-isomers exclusively.

Nucleophilic ring opening of aziridines with amines under catalyst- and solvent-free conditions

The aza-addition of aziridines to obtain vicinal-diamines was achieved under catalyst- and solvent-free conditions for the first time. Various aryl, alkyl and meso-bicyclic aziridines with a Ts-protecting group were tolerated, and aromatic amine-nucleophi