57704-54-8

Basic information

• Product Name: TERT-BUTYL 3-HYDROXYBENZOATE
• Synonyms: TERT-BUTYL 3-HYDROXYBENZOATE;3-Hydroxybenzoic acid tert-butyl ester
• CAS NO: 57704-54-8
• Molecular Formula: C₁₁H₁₄O₃
• Molecular Weight: 194.23
• Mol File: 57704-54-8.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 308.8±15.0 °C(Predicted)
• Appearance: /
• Density: 1.107±0.06 g/cm3(Predicted)
• PKA: 9.13±0.10(Predicted)
• CAS DataBase Reference: TERT-BUTYL 3-HYDROXYBENZOATE(CAS DataBase Reference)
• NIST Chemistry Reference: TERT-BUTYL 3-HYDROXYBENZOATE(57704-54-8)
• EPA Substance Registry System: TERT-BUTYL 3-HYDROXYBENZOATE(57704-54-8)

Safety Data

• Hazardous Substances Data: 57704-54-8(Hazardous Substances Data)

Upstream product

• 99-06-9 3-Carboxyphenol 
• 115-11-7 isobutene 
• 24424-99-5 di-tert-butyl dicarbonate 
• 36805-97-7 N,N-dimethylformamide di-tert-butyl acetal 
• 75-65-0 tert-butyl alcohol 

Downstream Products

• 330580-35-3 3-tert-butoxycarbonylphenyl chlorocarbonate 
• 929289-87-2 3-(3-tert-butoxycarbonyl-phenoxymethyl)-4-chloro-thieno[3,2-c]pyridine-7-carboxylic acid ethyl ester 
• 183157-68-8 (1R,3S)-1,2,2-trimethylcyclopentane-1,3-dicarboxylic aciddi(3-hydroxybenzoic acid) ester 
• 330580-38-6 tert-butyl 3-{[2-methyl-2-(phenylacetyl)hydrazino]carbonyloxy}benzoate 
• 330580-36-4 tert-butyl 3-{[2-(phenylacetyl)hydrazino]carbonyloxy}benzoate 
• 330580-40-0 tert-butyl 3-{[1-methyl-2-(phenylacetyl)hydrazino]carbonyloxy}benzoate 
• 330580-44-4 tert-butyl 3-[(2-benzoyl-2-methylhydrazino)carbonyloxy]benzoate 
• 330580-47-7 tert-butyl 3-[(2-benzoyl-1-methylhydrazino)carbonyloxy]benzoate 
• 330580-42-2 tert-butyl 3-{[2-(benzoyl)hydrazino]carbonyloxy}benzoate 
• 330580-37-5 3-{[2-(phenylacetyl)hydrazino]carbonyloxy}benzoic acid 
• 330580-39-7 3-{[2-methyl-2-(phenylacetyl)hydrazino]carbonyloxy}benzoic acid 
• 330580-41-1 3-{[1-methyl-2-(phenylacetyl)hydrazino]carbonyloxy}benzoic acid 
• 330580-48-8 3-[(2-benzoyl-1-methylhydrazino)carbonyloxy]benzoic acid 
• 330580-43-3 3-{[2-(benzoyl)hydrazino]carbonyloxy}benzoic acid 

Relevant articles and documents

MACROCYCLIC DIAMINE DERIVATIVES AS ENT INHIBITORS FOR THE TREATMENT OF CANCERS, AND COMBINATION THEREOF WITH ADENOSINE RECEPTOR ANTAGONISTS

The present invention relates to macrocyclic diamine derivatives of formula II, including pharmaceutically acceptable salts and solvates thereof. Compounds of the invention are inhibitors of ENT family transporter, especially of ENT1, and are useful as therapeutic compounds for the treatment of cancers. The invention also relates to the combined use of the macrocyclic diamine derivatives with an adenosine receptor antagonist, for the treatment of cancers.

4-amino-thieno[3,2-c] pyridine-7-carboxylic acid derivatives

The present invention relates to compounds of the formula medicaments containing them and the use of these compounds as pharmaceutically active agents. The compounds exhibit activity as Raf kinase inhibitors and therefore may be useful for the treatment of diseases mediated by said kinases, especially as anticancer agents.

Chiral carboxylic acid ligands derived from camphoric acid

Versatile and convenient preparations of chiral carboxylic acid ligands, derived from camphoric acid, are described, either by esterification of camphoric dichloride or by a regioselective opening of the corresponding anhydride by a variety of alcohols or diols.