57707-92-3

Upstream product

• 108-86-1 bromobenzene 
• 3391-90-0 (S)-(-)-pulegone 
• 89-79-2 (S)-2-Isopropenyl-5-methyl-cyclohexanol 
• 529-00-0 (S)-isopulegone 
• 7540-51-4 (S)-3,7-dimethyl-6-octen-1-ol 
• 5949-05-3 (S)-Citronellal 

Downstream Products

• 57707-91-2 (1S,2R,5S)-8-(+)-phenylmenthol 
• 122517-58-2 (-)-(1R,2S,5S)-5-Methyl-2-(1-methyl-1-phenylethyl)cyclohexanol 

Relevant academic research and scientific papers

Large-Scale Preparation of Pure (+)-(1S,2R,5S)-5-Methyl-2-(1-methyl-1-phenylethyl)cyclohexanol

A procedure is described for the preparation of (S)-(-)pulegone, (-)-1, starting from (S)-(-)citronellol, (-)-6, in a preparative scale.Compound (-)-1 can easily be converted into (+)-(1S,2R,5S)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexanol: (+)-2 by a procedure described in literature, which was simplified essentially.Now (+)-2 is accessible in larger amounts and thus is available as an efficient chiral auxiliary in stoichiometric asymmetric syntheses.