57744-46-4

Upstream product

• 881-90-3 4-benzylidene-2-methyl-2-oxazolin-5-one 
• 61-90-5 L-leucine 
• 34237-21-3 (L)-leucine sodium salt 
• 38879-46-8 (Z)-4-benzylidene-2-methyl-5(4H)-oxazolone 
• 118604-74-3 sodium salt of racemic leucine 
• 93509-88-7 Ac-ΔPhe-L-Leu-OH methyl ester 
• 143417-47-4 (4E)-2-methyl-4-(phenylmethylidene)-4,5-dihydro-1,3-oxazol-5-one 
• 328-39-2 LEUCINE 

Downstream Products

• 38155-16-7 Ac-(S)-Phe-(S)-Leu-OH 
• 38155-17-8 Ac-(R)-Phe-(S)-Leu-OH 
• 63-91-2 L-phenylalanine 
• 673-06-3 D-(R)-phenylalanine 
• 84255-95-8 Ac-ΔPhe-L-Leu-ΔVal-OEt 
• 93509-88-7 racemic Ac-ΔPhe-Leu-OMe 
• 38155-11-2 Ac-(S)-Phe-(S)-Leu-OMe 
• 38155-12-3 Ac-(R)-Phe-(S)-Leu-OMe 
• 181590-96-5 Ac-ΔPhe-(S)-Leu-OMe 

Relevant academic research and scientific papers

ASYMMETRIC HOMOGENOUS REDUCTION OF DEHYDROPEPTIDES

Monodehydropeptides with the dehydroaminoacid fragment in C-terminal or N-terminal position were synthetized as well as a family with the general formula Ac-ΔPhe-(Gly)n-Leu-OR (n = 0-2, R = H or Me).Asymmetric reduction of these compounds catalyzed by chiral rhodium complexes was investigated.The results were discussed in terms of double asymmetric induction.A method was developped to avoid the use of both enantiomers of the substrate or of the catalyst, it consists in the total reduction of a racemic dehydropeptide.The products distribution gives access to the two desired facial selectivities.

Dehydrooligopeptides. IV. Synthesis of Various Types of Dehydrodi- and tripeptides by Fragment Condensation and Base-Catalyzed β-Elimination

The synthesis of dehydrotripeptides, composed of an α-amino acid and two α-dehydroamino acid (DHA) residues, by the direct coupling of N-protected δ1-dehydrotripeptide with DHA ester and by the β-elimination od δ1-dehydrodipeptide co