5775-90-6

Usage

Uses

Used in Pharmaceutical Research:
Ethyl 4-bromo-1,5-dimethylpyrazole-3-carboxylate is used as a research compound for the development of potential drug candidates due to its diverse pharmacological properties.
Used in Organic Synthesis:
Ethyl 4-bromo-1,5-dimethylpyrazole-3-carboxylate is used as a synthetic intermediate in the preparation of various organic compounds.
Used in Antioxidant Applications:
Ethyl 4-bromo-1,5-dimethylpyrazole-3-carboxylate is used as an antioxidant agent, which can help protect cells from oxidative damage and may have potential applications in the prevention and treatment of various diseases.
Used in Anti-inflammatory Applications:
Ethyl 4-bromo-1,5-dimethylpyrazole-3-carboxylate is used as an anti-inflammatory agent, which can help reduce inflammation and may have potential applications in the treatment of inflammatory conditions.
Used in Antimicrobial Applications:
Ethyl 4-bromo-1,5-dimethylpyrazole-3-carboxylate is used as an antimicrobial agent, which can help inhibit the growth of microorganisms and may have potential applications in the treatment of infections.
Used in Disease Treatment:
Ethyl 4-bromo-1,5-dimethylpyrazole-3-carboxylate has been studied for its potential use in the treatment of various diseases and conditions, including its antioxidant, anti-inflammatory, and antimicrobial properties.

Upstream product

• 4027-57-0 ethyl 5-methyl-1H-pyrazole-3-carboxylate 
• 6076-14-8 4-bromo-5-methyl-1H-pyrazole-3-carboxylic acid ethyl ester 
• 74-88-4 methyl iodide 
• 5744-51-4 ethyl 1,5-dimethyl-1H-pyrazole-3-carboxylate 

Downstream Products

• 1006471-24-4 4-bromo-1,5-dimethylpyrazole-3-carbonyl chloride 
• 5775-91-7 4-bromo-1,5-dimethyl-1H-pyrazole-3-carboxylic acid 

Relevant academic research and scientific papers

2-AZABICYCLO[3.1.1] DERIVATIVES AS ANTAGONISTS OF THE OREXIN-1 AND OREXIN-2 RECEPTORS

There is provided a compound of formula I, wherein L1, R1, R2, R5, X, A and B have meanings given in the description, and pharmaceutically acceptable salts, solvates and prodrugs thereof, which compounds are useful as antagonists of the orexin-1 and orexin-2 receptors or as selective antagonists of the orexin-1 receptor, and thus, in particular, in the treatment or prevention of inter alia substance dependence, addiction, anxiety disorders, panic disorders, binge eating, compulsive disorders, impulse control disorders, cognitive impairment and Alzheimer's disease.

MACROCYCLIC CHLORINE SUBSTITUTED INDOLE DERIVATIVES

The present invention relates to macrocyclic indole derivatives of general formula (I) : (I), in which R1, R2, R3, R4, R5, R6, A and L are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds, and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative disorders, as a sole agent or in combination with other active 10 ingredients.

MACROCYCLIC INDOLE DERIVATIVES

The present invention relates to macrocyclic indole derivatives of general formula (I), in which R1, R2, R3, R4, R5, R6, A and L are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds, and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative disorders, as a sole agent or in combination with other active ingredients.

ARYL ANNULATED MACROCYCLIC INDOLE DERIVATIVES

The present invention relates to aryl annulated macrocyclic indole derivatives of general formula (I): in which R1, R2, R3, R4, R5, R6, A and L are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds, and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative disorders, as a sole agent or in combination with other active ingredients.

MACROCYCLIC CHLORINE SUBSTITUTED INDOLE DERIVATIVES

The present invention relates to macrocyclic indole derivatives of general formula (I) : in which R1, R2, R3, R4, R5, R6, A and L are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds, and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative disorders, as a sole agent or in combination with other active ingredients.

MACROCYCLIC FLUORINE SUBSTITUTED INDOLE DERIVATIVES AS MCL-1 INHIBITORS, FOR USE IN THE TREATMENT OF CANCER

The present invention relates to macrocyclic indole derivatives of general formula (I) : in which R1, R2, R3, R4, R5, R6, A and L are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds, and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative disorders, as a sole agent or in combination with other active ingredients.

SUBSTITUTED MACROCYCLIC INDOLE DERIVATIVES

The present invention relates to substituted macrocyclic indole derivatives of general formula (I) in which R1, R2, R3, R4, R5, R6, A and L are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds, and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative disorders, as a sole agent or in combination with other active ingredients.

MACROCYCLIC INDOLE DERIVATIVES

The present invention relates to macrocyclic indole derivatives of general formula (I) : (I), in which R1, R2, R3, R4, R5, R6, A and L are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds, and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative disorders, as a sole agent or in combination with other active ingredients.