6076-14-8

Usage

Uses

Used in Chemical Synthesis:
Ethyl 4-bromo-5-methyl-1H-pyrazole-3-carboxylate is used as a starting material for the synthesis of various chemical compounds. Its reactivity and unique structure make it a valuable component in the creation of new molecules with potential applications in different industries.
Used in Pharmaceutical Research:
Ethyl 4-bromo-5-methyl-1H-pyrazole-3-carboxylate is used as a building block in the development of new pharmaceutical compounds. Its chemical properties allow for the creation of potential drug candidates that could be used in the treatment of various diseases and conditions.
Used in Material Science:
Ethyl 4-bromo-5-methyl-1H-pyrazole-3-carboxylate is used as a component in the development of new materials with specific properties. Its inclusion in the synthesis process can lead to the creation of materials with unique characteristics that could be applied in various fields, such as electronics or advanced materials research.
Used in Laboratory Research:
Ethyl 4-bromo-5-methyl-1H-pyrazole-3-carboxylate is used as a reagent in various laboratory experiments and studies. Its reactivity and chemical properties make it a useful tool for researchers exploring new chemical reactions and processes.

Upstream product

• 94993-81-4 4-amino-5-methyl-1⁽²⁾H-pyrazole-3-carboxylic acid 
• 5334-38-3 3-methyl-4-nitropyrazole-5-carboxylic acid 
• 4027-57-0 ethyl 5-methyl-1H-pyrazole-3-carboxylate 
• 64-17-5 ethanol 
• 82231-52-5 4-bromo-5-methyl-1⁽²⁾H-pyrazole-3-carboxylic acid 

Downstream Products

• 1043909-04-1 4-bromo-5-methyl-1(2)H-pyrazole-3-carboxylic acid hydrazide 
• 5775-90-6 ethyl 4-bromo-1,5-d imethyl-1H-pyrazole-3-carboxylate 
• 1126779-45-0 Ethyl 4-bromo-1-[4-(tert-butoxycarbonyl)benzyl]-5-methyl-1H-pyrazole-3-carboxylate 
• 1019403-65-6 4-bromo-1-[(4-chlorophenylcarbamoyl)-methyl]-5-methyl-1H-pyrazole-3-carboxylic acid ethyl ester 
• 1019403-42-9 C₁₅H₁₅BrClN₃O₃ 

Relevant academic research and scientific papers

2-AZABICYCLO[3.1.1] DERIVATIVES AS ANTAGONISTS OF THE OREXIN-1 AND OREXIN-2 RECEPTORS

There is provided a compound of formula I, wherein L1, R1, R2, R5, X, A and B have meanings given in the description, and pharmaceutically acceptable salts, solvates and prodrugs thereof, which compounds are useful as antagonists of the orexin-1 and orexin-2 receptors or as selective antagonists of the orexin-1 receptor, and thus, in particular, in the treatment or prevention of inter alia substance dependence, addiction, anxiety disorders, panic disorders, binge eating, compulsive disorders, impulse control disorders, cognitive impairment and Alzheimer's disease.

ISOQUINOLINES AS INHIBITORS OF HPK1

Isoquinoline compounds and their use as inhibitors of HPK1 (hematopoietic kinase 1) are described. The compounds are useful in treating HPK1-dependent disorders and enhancing an immune response. Also described are methods of inhibitng HPK1, methods of treating HPK1-dependent disorders, methods for enhancing an immune response, and methods for preparing the isoquinoline compounds.

1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists

A new series of 1,3-dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives has been identified as potent A2B adenosine receptor antagonists. The products have been evaluated for their binding affinities for the human A2B, A1, A2A, and A3 adenosine receptors. N-(4-chloro-phenyl)-2-[3-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-5-methyl-pyrazol-1-yl] (11c) showed a high affinity for the human A2B adenosine receptor Ki = 7 nM and good selectivity (A1, A2A, A3/A2B > 140). Synthesis and SAR of this novel class of compounds is presented herein.