57758-55-1

Basic information

• Product Name: 1H-Pyrrole-3-carboxylic acid, 4-hydroxy-2-methyl-5-phenyl-, methyl ester
• CAS NO: 57758-55-1
• Molecular Formula: C13H13NO3
• Molecular Weight: 231.251
• Mol File: 57758-55-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1H-Pyrrole-3-carboxylic acid, 4-hydroxy-2-methyl-5-phenyl-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole-3-carboxylic acid, 4-hydroxy-2-methyl-5-phenyl-, methyl ester(57758-55-1)
• EPA Substance Registry System: 1H-Pyrrole-3-carboxylic acid, 4-hydroxy-2-methyl-5-phenyl-, methyl ester(57758-55-1)

Safety Data

• Hazardous Substances Data: 57758-55-1(Hazardous Substances Data)

Upstream product

• 1074-12-0 phenylglyoxal hydrate 
• 21731-17-9 methyl 3-aminocrotonate 
• 14205-39-1 methyl (E)-3-aminocrotonate 
• 105-45-3 acetoacetic acid methyl ester 
• 1075-06-5 2,2-dihydroxy-1-phenyl-ethanone 
• 14205-39-1 methyl 3-aminocrotonate 
• 24461-61-8 phenylglycine methyl ester 

Downstream Products

• 91480-99-8 methyl 4-acetoxy-2-methyl-5-phenylpyrrol-3-yl-carboxylate 

Relevant articles and documents

N-substituted pyrrolinones from enamines and α-dicarbonyls

The reaction between N-substituted enamines and phenylglyoxal or glyoxal yielded Δ2-pyrrolin-5-ones in moderate to good yields. An uncommon pyrrolo [2,1-b]thiazole derivative was formed as a minor product when a N-(2-mercaptoethyl)enamine was used as the starting reagent. An explanation for the regiochemistry of the reaction is proposed.

Novel one-pot, three-component synthesis of new 2-alkyl-5-aryl-(1H)- pyrrole-4-ol in water

(Chemical Equation Presented) New 2-alkyl-5-aryl-(1H)-pyrrole-4-ol derivatives were synthesized via three-component reaction of β-dicarbonyl compounds with arylglyoxals in the presence of ammonium acetate in water at room temperature.

Synthesis and pharmacological evaluation of a series of analgesic and antiinflammatory 4-aminopyrroles

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