57770-65-7Relevant academic research and scientific papers
Reactions with heterocyclic amidines: Synthesis of pyrazolo[3,4-e]thiazepine, pyrazolo[1,5-c] 1,2,4-triazine and pyrazolo[1,5-a]pyrimidine derivatives
Sofan,El-Taweel,Abu El-Maati,El-Agamey
, p. 482 - 486 (2007/10/02)
5-Aminopyrazoles 1 condensed with aromatic aldehydes in C2H5OH/piperidine to afford the arylidenes 3a-e. Compounds 3 reacted with mercaptoacetic acid to give the pyrazolo[3,4-e] 1,4-thiazepines 5a, d. Diazotized aminopyrazole 1a coupled with acetoacetanilide to afford the parazolo[1,5-c] 1,2,4-triazine 6. Reaction of 1a with the ylidenes 7a-d afforded 13a-c and 16, respectively. Also, condensation of 18 with ethyl acetoacetate, acetoacetanilide, ethyl α-methylacetoacetate and diethyl acetonedicarboxylate resulted in the formation of the pyrazolopyrimidines 22a-c.
