57777-56-7

Upstream product

• 31737-09-4 6-chloro-1-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 
• 100-52-7 benzaldehyde 
• 183006-44-2 6-benzylidenehydrazino-1-methyluracil 

Downstream Products

• 76278-59-6 3-Ethyl-1-methyl-6-phenyl-7-azalumazine 
• 76278-60-9 1-Methyl-6-phenyl-3-propyl-7-azalumazine 
• 76278-77-8 9-Butyl-7-methyl-2-phenyl-6-azapurin-8-one 
• 76278-75-6 7-Methyl-2-phenyl-9-propyl-6-azapurin-8-one 
• 76278-76-7 7-Methyl-2-phenyl-9-(2-propyl)-6-azapurin-8-one 
• 76278-74-5 9-Ethyl-7-methyl-2-phenyl-6-azapurin-8-one 
• 76278-62-1 3-Butyl-1-methyl-6-phenyl-7-azalumazine 
• 76278-61-0 1-Methyl-6-phenyl-3-(2-propyl)-7-azalumazine 

Relevant academic research and scientific papers

Fervenulin, 4-Deazafervenulin and 5-Deazaalloxazine Analogues. Synthesis and Antimicrobial Activity

6-Chloro-1-methyluracil 1 was converted to 6-hydrazino- 2, and/or 6-arylamino-1-methyluracils 3a-d.Condensation of 2 with aldehydes led to the corresponding 6-hydrazones 4a-c.Cyclization of 2 with benzil provided 4-deaza-6-demethyl fervenulin 6.Refluxing 4a-c with NaNO2/AcOH afforded 4-deazafervenulins analogues 7a-c, the nitrosation of compound 2 provided 6-azido-1-methyluracil 8.The formylation of 3a-d by Vilsmeier reagent afforded 5-deazaalloxazines 10a-d.Reaction of 1 with cyanoacetic acid hydrazide led to the formation of 11. - Keywords: 6-chloro-1-methyluracil; 6-demethyl fervenulin; 5-deazaalloxazin