577784-63-5Relevant academic research and scientific papers
Copper reagents: A new and efficient solution for the selective addition of metallated propargylic amines to aldehydes
Bernaud, Frederic,Vrancken, Emmanuel,Mangeney, Pierre
, p. 2567 - 2569 (2003)
(Matrix presented) Anti α-amino-homopropargylic alcohols are prepared by addition of metallated propargylic amines to aldehydes. Among the four organometallic (Ll, Zn, Ti, Cu) derivatives used, the most effective are the copper reagents.
Nicholas reactions of amines
Roth, Klaus-Dieter,Mueller, Utz
, p. 2919 - 2922 (2007/10/02)
An efficient synthesis of mono- and bispropargylated tertiary amines is described, using the Nicholas reaction with primary and secondary amines as nucleophiles.
