577793-68-1

Upstream product

• 577793-67-0 tert-butyl-(5-ethoxy-2-fluoro-phenoxy)-dimethyl-silane 
• 68-12-2 N,N-dimethyl-formamide 
• 459-26-7 4-ethoxy-1-fluorobenzene 
• 577793-66-9 5-ethoxy-2-fluoro-phenol 

Downstream Products

• 376601-44-4 (4-cyano-phenylamino)-(5-ethoxy-2-fluoro-3-hydroxy-phenyl)-acetic acid ethyl ester 
• 906079-97-8 (4-cyano-phenylamino)-[3-ethoxy-2-fluoro-5-(tetrahydro-furan-3-yloxy)-phenyl]-acetic acid ethyl ester 
• 376601-45-5 (4-cyano-phenylamino)-{3-ethoxy-2-fluoro-5-[(R)-tetrahydro-furan-3-yloxy]-phenyl}-acetic acid ethyl ester 
• 891842-67-4 (3-(tert-butyldimethylsilyloxy)-5-ethoxy-2-fluorophenyl)(4-phenyl-1-trityl-1H-imidazol-2-yl)methanol 
• 1147347-74-7 5-ethoxy-2-fluoro-3-hydroxybenzaldehyde 

Relevant academic research and scientific papers

Dose-dependent antithrombotic activity of an orally active tissue factor/factor VIIa inhibitor without concomitant enhancement of bleeding propensity

The discovery of a highly potent and selective tissue factor/factor VIIa inhibitor is described. Upon oral administration of its double prodrug in the guinea pig, a dose-dependent antithrombotic effect is observed in an established model of arterial throm