57783-80-9Relevant academic research and scientific papers
Regioselective removal of the anomeric O-benzyl from differentially protected carbohydrates
Jalsa, Nigel Kevin
, p. 6587 - 6590 (2012/02/03)
A mild, regioselective deprotection of the anomeric O-benzyl from multi-functionally protected carbohydrates via catalytic transfer hydrogenation is described. The protocol is tolerant of O-benzyl and O-benzylidene protections at non-anomeric positions, g
A strategy for chemical synthesis of selectively methyl-esterified oligomers of galacturonic acid
Clausen, Mads H.,Jorgensen, Malene R.,Thorsen, Jesper,Madsen, Robert
, p. 543 - 551 (2007/10/03)
The synthesis of monomethyl-esterified trigalacturonans 1-3 is described as part of a general strategy towards pectic oligosaccharides. The necessary monomeric building blocks were all prepared on a large scale from galactose pentaacetate. The glycosylations were carried out between galactose glycosyl donors and acceptors using the n-pentenyl glycosylation technique. Yields of the desired α-anomers were in the 50 to 74% range. The trigalactans thus obtained were then subjected to oxidation at C-6. Depending on the protecting group at this position the oxidation either produced the carboxylic acid or the corresponding methyl ester. Hereby, oligomers of galacturonic acid can be prepared with methyl esters introduced in a regiocontrolled fashion.
Syntheses of trehazolin derivatives and evaluation as glycosidase inhibitors
Kobayashi,Shiozaki,Ando
, p. 2570 - 2580 (2007/10/02)
The trehazolin derivatives 9-12 were synthesized from the aminocyclitol (7), which is the degradation product of trehazolin (5). In particular, compounds 9-11 were pseudodisaccharides that underwent replacement of the corresponding nonreducing D-glucose m
