577957-02-9

Basic information

• Product Name: BENZIMIDAZOLE-4-CARBOXYLIC ACID 2-ETHOXY ETHYL ESTER
• Synonyms: BENZIMIDAZOLE-4-CARBOXYLIC ACID 2-ETHOXY ETHYL ESTER;ethyl 2-ethoxy-3H-benzimidazole-4-carboxylate;NZIMIDAZOLE-4-CARBOXYLIC ACID 2-ETHOXY ETHYL ESTER;BENZIMIDAZOLE-4-CARBOXYLIC ACID 2-ETHOXY ETHYL ESTER（WS204232）
• CAS NO: 577957-02-9
• Molecular Formula: C₁₂H₁₄N₂O₃
• Molecular Weight: 234.25116
• Mol File: 577957-02-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 384.1±34.0 °C(Predicted)
• Appearance: /
• Density: 1.232±0.06 g/cm3(Predicted)
• PKA: 8.41±0.30(Predicted)
• CAS DataBase Reference: BENZIMIDAZOLE-4-CARBOXYLIC ACID 2-ETHOXY ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: BENZIMIDAZOLE-4-CARBOXYLIC ACID 2-ETHOXY ETHYL ESTER(577957-02-9)
• EPA Substance Registry System: BENZIMIDAZOLE-4-CARBOXYLIC ACID 2-ETHOXY ETHYL ESTER(577957-02-9)

Safety Data

• Hazardous Substances Data: 577957-02-9(Hazardous Substances Data)

Upstream product

• 78-09-1 orthocarbonic acid tetraethyl ester 
• 61063-11-4 2-Amino-3-nitrobenzoic acid,ethyl ester 
• 136285-65-9 ethyl 2-[(N-tert-butoxycarbonyl)amino]-3-nitrobenzoate 
• 37466-88-9 2,3-Diaminobenzoic acid,ethyl ester 

Relevant articles and documents

A facile one-pot synthesis of benzimidazoles from 2-nitroanilines by reductive cyclization

A facile one-pot process to prepare benzimidazole derivatives is described. Reductive cyclization of a serial of 2-nitroanilines with orthoesters in the presence of Pd/C in methanol at room temperature, which is promoted by a catalytic amount of acetic acid, affords the corresponding benzimidazole derivatives in high yields.