577969-78-9

Upstream product

• 577969-74-5 (4R,5R)-5-(N-allyl-tert-butoxycarbonylamino)-2,2-dimethyl-4-vinyl-1,3-dioxolane 
• 577969-73-4 (4aR,8aR)-5-tert-butoxycarbonyl-2,2-dimethyl-4,4a,6,8a-tetrahydro[1,3]dioxino[5,4-b]pyridine 
• 577969-75-6 (1S,3aR,7aS,8S)-3-tert-butoxycarbonyl-6,6-dimethyl-1a,2,3a,4,7a,7b-hexahydro-1,3,5-trioxa-3-azacyclopropa[a]naphthalene 

Relevant academic research and scientific papers

Concise and highly stereocontrolled synthesis of 1-deoxygalactonojirimycin and its congeners using dioxanylpiperidene, a promising chiral building block

(Matrix presented) A concise and stereoselective synthesis of the chiral building block, dioxanylpiperidene 4 as a precursor for deoxyazasugars, starting from the Garner aldehyde 5 using catalytic ring-closing metathesis (RCM) for the construction of the piperidine ring is described. The asymmetric synthesis of 1-deoxygalactonojirimycin and its congeners 1-3 was carried out via the use of 4 in a highly stereocontrolled mode.