57822-29-4Relevant academic research and scientific papers
PtCl2-catalyzed rearrangement of methylenecyclopropanes
Fuerstner, Alois,Aissa, Christophe
, p. 6306 - 6307 (2007/10/03)
Alkylidenecyclopropanes readily convert into cyclobutene derivatives on treatment with catalytic amounts of PtCl2. The reaction is strongly accelerated when performed under an atmosphere of CO (1 atm). The resulting cyclobutenes are isolated in
Zirconium-Mediated Cross-Coupling of Terminal Alkynes and Vinyl Bromides: Selective Synthesis of Cyclobutene and 1,3-Diene Derivatives
Barluenga, Jose,Rodriguez, Felix,Alvarez-Rodrigo, Lucia,Fananas, Francisco J.
, p. 101 - 108 (2007/10/03)
A diastereoselective synthesis of 1,3-butadiene or cyclobutene derivatives by a zirconium-mediated reaction of alkenyllithium compounds and vinyl bromides is reported. The key steps involve the generation of zirconocene-alkyne complexes from haloalkenes and subsequent coupling with alkenyl bromides. Thus, formally the process supposes the cross-coupling reaction between a terminal alkyne and an alkenyl bromide. Moreover, the use of butyl vinyl ether instead of vinyl bromide as the unsaturated system allows an alternative access to different 1,3-butadiene regioisomers.
