57830-48-5 Usage
Uses
Used in Pharmaceutical and Agrochemical Industries:
2-(TRIFLUOROMETHYLTHIO)BENZALDEHYDE is used as a chemical intermediate for the synthesis of various pharmaceuticals and agrochemicals. Its reactivity allows it to be a key component in the production of a range of medicinal and agricultural products, contributing to the development of new and effective treatments and solutions.
Used in the Food Industry:
In the food industry, 2-(TRIFLUOROMETHYLTHIO)BENZALDEHYDE is utilized as a flavoring agent. Its unique properties contribute to the creation of specific tastes and scents in food products, enhancing the overall sensory experience for consumers.
Safety Considerations:
It is crucial to handle 2-(TRIFLUOROMETHYLTHIO)BENZALDEHYDE with care due to its potential hazards. Ingestion or inhalation of the compound can be harmful, and it may cause skin and eye irritation upon contact. Adequate safety measures should be taken during its production, storage, and use to minimize risks to human health and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 57830-48-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,8,3 and 0 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 57830-48:
(7*5)+(6*7)+(5*8)+(4*3)+(3*0)+(2*4)+(1*8)=145
145 % 10 = 5
So 57830-48-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H5S2.BF4/c1-2-4-7-6(3-1)8-5-9-7;2-1(3,4)5/h1-5H;/q+1;-1
57830-48-5Relevant academic research and scientific papers
Ligandless Nickel-Catalyzed Ortho-Selective Directed Trifluoromethylthiolation of Aryl Chlorides and Bromides Using AgSCF3
Nguyen, Tin,Chiu, Weiling,Wang, Xinying,Sattler, Madeleine O.,Love, Jennifer A.
supporting information, p. 5492 - 5495 (2016/11/17)
A mild protocol for Ni-catalyzed trifluoromethylthiolation of aryl chlorides and bromides is described herein. The method utilizes AgSCF3 as an easily accessible nucleophilic trifluoromethylthiolating reagent and does not require any ligands or additives. Ortho-selectivity is achieved using a variety of directing groups such as imines, pyridines, and oxazolines for 24 examples in up to 95% yield.
Copper-catalyzed trifluoromethylthiolation of aryl halides with diverse directing groups
Xu, Jiabin,Mu, Xin,Chen, Pinhong,Ye, Jinxing,Liu, Guosheng
supporting information, p. 3942 - 3945 (2014/08/18)
The expansion of cross-coupling components in Cu-catalyzed C-X bond forming reactions have received much attention recently. A novel Cu-catalyzed trifluoromethylthiolation of aryl bromides and iodides with the assistance of versatile directing groups such as pyridyl, methyl ester, amide, imine and oxime was reported. CuBr was used as the catalyst, and 1,10-phenanthroline as the ligand. By changing the solvent from acetonitrile to DMF, the coupling process could even take place at room temperature.
