3872-23-9

Basic information

• Product Name: COPPER TRIFLUOROMETHANETHIOL
• Synonyms: COPPER(I)TRIFLUOROMETHANETHIOL;COPPER(I) TRIFLUOROMETHANETHIOLATE;COPPER TRIFLUOROMETHANETHIOL;TRIFLUOROMETHYLTHIOCOPPER;Trifluoromethylthio copper(l);Copper(Ⅰ)trifluoromethanethiol;Copper trifluoromethanethiol 80%;Coppertrifluoromethanethiol80%
• CAS NO: 3872-23-9
• Molecular Formula: CF₃S*Cu
• Molecular Weight: 164.62
• EINECS: 808-179-4
• Product Categories: Classes of Metal Compounds;Cu (Copper) Compounds;Sulfur Compounds (for Synthesis);Synthetic Organic Chemistry;Transition Metal Compounds
• Mol File: 3872-23-9.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: 0-10°C
• Solubility: Acetonitrile (Sparingly)
• Stability: Air Sensitive, Hygroscopic, Moisture Sensitive
• CAS DataBase Reference: COPPER TRIFLUOROMETHANETHIOL(CAS DataBase Reference)
• NIST Chemistry Reference: COPPER TRIFLUOROMETHANETHIOL(3872-23-9)
• EPA Substance Registry System: COPPER TRIFLUOROMETHANETHIOL(3872-23-9)

Safety Data

• Hazard Codes: T
• Statements: 20/21/22
• Safety Statements: 22-36/37/39
• Hazardous Substances Data: 3872-23-9(Hazardous Substances Data)

Usage

Uses

Copper(I) Trifluoromethanethiolate is useful for the synthesis of (trifluoromethylthiomethyl/trifluoromethylsulfonylmethyl)dihydropyrazoles.

InChI:InChI=1/CHF3S.Cu/c2-1(3,4)5;/h5H;/q;+1/p-1/rCCuF3S/c2-6-1(3,4)5

Upstream product

• 7681-65-4 copper(l) iodide 
• 811-68-7 silver(I) trifluoromethanethiolate 
• 7787-70-4 copper(I) bromide 

Downstream Products

• 403-66-7 p-nitrophenyl trifluoromethyl sulfide 
• 456-56-4 phenyl trifluoromethylsulfide 
• 382-24-1 1,1,1,3,3,3-hexafluoro-2-trifluoromethyl-propane 
• 39902-62-0 2,2,3,3-tetra(trifluoromethyl)-perfluorobutane 
• 398-74-3 (2-chlorophenyl)(trifluoromethyl)sulfane 
• 447-60-9 2-(trifluoromethyl)benzonitrile 
• 75169-01-6 2,6-bis(trifluoromethylthio)-4-nitrophenol 
• 75169-02-7 2,6-bis(trifluoromethylthio)-4-nitroanisole 
• 2002-89-3 {2-[(trifluoromethyl)sulfanyl]ethynyl}benzene 
• 57830-48-5 2-((trifluoromethyl)thio)benzaldehyde 
• 88489-59-2 methyl 3-[(trifluoromethyl)sulfanyl]benzoate 
• 56-23-5 tetrachloromethane 
• 371-73-3 trifluoromethylmercaptothiocarbonyl fluoride 
• 681-87-8 tetrakis(trifluoromethylmercapto)methane 

Relevant articles and documents

Trifluoromethylthiolation of Unsymmetrical λ3-Iodane Derivatives: Additive-Free, Selective and Scalable Introduction of the SCF3 Group

The reaction of copper trifluoromethyl sulfide with diaryliodonium salts provides a straightforward pathway for the synthesis of aryl trifluoromethyl thioethers under mild reaction conditions and within short reaction times. High chemoselectivity was achieved by using mesityl as a leaving group. A large range of novel [(het)aryl](mesityl)iodonium salts underwent this reaction under the optimized conditions to give the desired products in moderate to good yields.

Direct trifluoromethylthiolation of alcohols under mild reaction conditions: Conversion of R-OH into R-SCF3

A direct process for the trifluoromethylthiolation of allylic and benzylic alcohols under mild conditions has been developed. A wide range of free alcohols underwent nucleophilic substitution in the presence of stable CuSCF3 and BF3·Et2O to give the corresponding products in good to excellent yields.