5791-90-2Relevant academic research and scientific papers
A Gold(I) Complex with a 1,1′-Binaphthyl-Substituted Diphosphene: Synthesis, Structure, and Catalytic Application to Intramolecular Hydroarylation Reactions
Kamikawa, Ken,Tsurusaki, Akihiro,Ura, Rikako
, (2019)
A gold(I) complex with a 1,1′-binaphthyl-substituted diphosphene was synthesized and fully characterized. A phosphorus atom with a less-hindered binaphthyl group coordinates to a gold(I) moiety in an η1 fashion. Both experiment and theoretical calculations supported the facile rotation around the C(Naph)-P bond in neutral and cationic diphosphene-gold(I) complexes. The newly obtained complex 2 was applied to the intramolecular hydroarylation of aryl propynyl ethers 5, and 2H-chromenes 6 were formed in 83-94% yield. Furthermore, the chiral diphosphene-gold(I) complex (S)-2 was used in the atropselective reaction to furnish 6b,c with up to 9% ee, which is the first example of the use of a diphosphene as a ligand for the transition-metal-catalyzed organic transformation.
2-aminoethyl-benzofuran derivatives, preparation thereof and therapeutical use thereof
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, (2011/05/18)
PCT No. PCT/FR97/00383 Sec. 371 Date Aug. 31, 1998 Sec. 102(e) Date Aug. 31, 1998 PCT Filed Mar. 5, 1997 PCT Pub. No. WO97/32870 PCT Pub. Date Sep. 12, 1997Compounds of formula (I), wherein A is a hydrogen atom or a hydroxyl group; B is a hydrogen atom or
Benzylamine derivatives, their preparation and their application in therapeutics
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, (2008/06/13)
Compounds of general formula (I) STR1 in which: A represents either a hydrogen atom, a hydroxyl, a C1-6 hydroxyalkyl group, a thiol, a C1-6 alkylsulphanyl group, an amino group, a C1-6 alkylamino group, a di(C1-6/sub
